Sericotropin: an Insect Neurohormonal Factor Affecting Rna Transcription
Sericotropin: an Insect Neurohormonal Factor Affecting Rna Transcription
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Sericotropin：一种影响 RNA 转录的昆虫神经激素因子
DOI：
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发表时间：
1994
期刊：
影响因子：
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通讯作者：
F. Sehnal
中科院分区：
文献类型：
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作者：
D. Kodrík;V. Filippov;M. Filippova;F. Sehnal
大蜡蛾 (Galleria mellonella) 的 Sericotropin 基因在大脑中表达，编码 133 个氨基酸，其中 16 个被鉴定为信号肽。受测试的鳞翅目昆虫和甲虫（但其他几种昆虫除外）的脑提取物含有约 10 kDa 的蛋白质，该蛋白质可被抗促肾上腺皮质激素抗血清识别。部分纯化的 Galleria 脑提取物和包含促丝蛋白 N 末端前 18 个氨基酸的合成肽可刺激外植丝腺中的 RNA 合成。
Sericotropin gene of the wax moth, Galleria mellonella, which is expressed in the brain, encodes for 133 amino acids of which 16 were identified as the signal peptide. Brain extracts of tested lepidopterans and a beetle, but not several other insects, contain a protein of about 10 kDa that is recognized by an anti-sericotropin antiserum. Partially purified Galleria brain extracts and a synthetic peptide comprising the first 18 amino acids of the sericotropin N-terminus stimulate RNA synthesis in explanted silk glands.