Renal function and water metabolism in the dromedary.
Renal function and water metabolism in the dromedary.
复制标题
单峰骆驼的肾功能和水代谢。
DOI：
10.1159/000421922
复制
发表时间：
1993
影响因子：
--
通讯作者：
R. Yagil
中科院分区：
文献类型：
--
作者：
R. Yagil
材料和方法所有关于肾脏生理和泌乳的研究都是在 15 只骆驼 (C. dromedarius) 群上进行的。这些动物被关在内盖夫本古里安大学的一个院子里。他们喂食干花生干草，以控制水的摄入量。夏季的阴凉处温度平均为 39°C。在随意给水和严格禁水 10 天后对所有动物进行检查。为了进行肾脏研究，将骆驼轻轻束缚（它们可以站立或蹲下），并将 18 号 Foley 导管引入它们的膀胱。通过颈静脉采血并输注。通过在脱水或补水之前以及氚消失后对血液进行标记，或者通过在饮用放射性水后检查血液中氚的出现来进行对注射氚的去向的研究[6]。一个特殊项目是葡萄糖耐量测试，当注入葡萄糖溶液时测试对葡萄糖负荷的反应[7]。体重通过大型动物秤（Peles，以色列）称重来确定。关于特定主题的文章中详细描述了血液和尿液中电解质和激素的测定。一般来说，该方法与人类研究中使用的方法密切相关。
Materials and MethodsAll the research on renal physiology and lactation was carried out on a herd of 15 camels (C. dromedarius). The animals were kept penned in a yard in the Ben-Gurion University of the Negev. They were fed a diet of dry peanut hay in order to control their water intake. The air shade temperatures in the summer averaged 39 C. The animals were all examined when water was given ad libitum and following 10 days of strict water deprivation.For the renal studies the camels were restrained lightly (they could stand or squat) and No. 18 Foley catheters were introduced into their bladders. Blood was taken and infusions given via the jugular veins. Studies on the fate of injected tritium were carried out by either marking the blood prior to dehydration or rehydration, and following the disappearance of tritium, or by examining the appearance of tritium in blood after drinking radioactive water [6]. A special project was the glucose tolerance test when dextrose solutions were infused to test the reaction to glucose loading [7]. Body weight was determined by weighing on a large animal scale (Peles, Israel). Detailed descriptions of the determinations of electrolytes and hormones in blood and urine were presented in the articles on the specific subject. In general the methodology closely followed that used in human studies.