Choosing two points to add to the 24-2 pattern to better describe macular visual field damage due to glaucoma
Choosing two points to add to the 24-2 pattern to better describe macular visual field damage due to glaucoma
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DOI：
10.1136/bjophthalmol-2014-306431
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发表时间：
2015-09-01
影响因子：
4.1
通讯作者：
Turpin, Andrew
中科院分区：
文献类型：
--
作者：
Chen, Siyuan;McKendrick, Allison M.;Turpin, Andrew
背景/目的 最近的一项研究表明，黄斑区的旁中央上视野经常受到青光眼的影响，并建议应在 Humphrey 24-2 视野测试模式中添加中央 10 度内的两个测试位置以检测此类损伤。本研究采用不同视野测试模式收集的数据来确定是否支持相同的两个测试位置作为有关视野丧失的最具信息性的信息。方法 62 名青光眼患者和 48 名对照者的数据集在 Medmont 视野计 M700（中央阈值或青光眼测试）上进行了视野评估。视野中心 10 度内的 12 个 24-2 位置是通过对 Medmont 数据的最近邻点进行插值得出的。如果青光眼组中央 10 度的剩余 24 个 Medmont 位置的阈值落在对照组同一位置的年龄校正值的下 5 个百分位之外，则将其标记为异常。然后，通过计算一对中具有 0、1 或 2 个异常位置的患者数量，评估 24 个位置的所有可能对的诊断能力。结果 绝大多数情况下，上黄斑区的位置对比下黄斑区的位置对更常出现异常。大约 50 对位置具有同等的检测损伤的能力，其中最好的一对有 74% 的患者至少有一个位置异常，52% 的患者两者都异常。 结论 在汉弗莱视野 24-2 模式的黄斑上区添加一对位置会增加青光眼患者中发现的异常位置的数量。
Background/aims A recent study has shown that the paracentral upper visual field in the macular region is often affected in glaucoma and suggested that two test locations within the central 10 degrees should be added to the Humphrey 24-2 visual field test pattern to detect such damage. This study employed data collected using a different visual field test pattern to determine whether the same two-test locations are supported as the most informative regarding visual field loss.Methods A data set of 62 patients with glaucoma and 48 controls had visual field assessments on the Medmont perimeter M700 (Central Threshold or Glaucoma test). Twelve 24-2 locations within central 10 degrees of visual field were derived by interpolation of the nearest neighbours of the Medmont data. The remaining 24 Medmont locations in the central 10 degrees of the glaucomatous set were labelled as abnormal if their thresholds fell outside the lower 5th centile of the age-corrected values for the same location from the control group. All possible pairs of the 24 locations were then assessed for diagnostic power by counting the number of patients that had 0, 1 or 2 abnormal locations in a pair.Results Overwhelmingly, pairs of locations in the superior macular region were more often abnormal than pairs in the inferior. About 50 pairs of locations had equivalent ability to detect damage, with the best pair having 74% of patients with at least one of the locations as abnormal, and 52% both.Conclusions Adding a pair of locations to the superior macular region of the Humphrey Visual Field 24-2 pattern increases the number of abnormal locations identified in individuals with glaucoma.