Capture-recapture is a potentially useful method for assessing publication bias

Capture-recapture is a potentially useful method for assessing publication bias
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DOI:
10.1016/j.jclinepi.2003.09.015
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发表时间:
2004-04-01
影响因子:
7.2
通讯作者:
Anderson, CS
Anderson, CS
中科院分区:
医学2区
文献类型:
--
作者:
Bennett, DA;Latham, NK;Anderson, CS

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目标:发表偏倚是随机对照试验系统评价中的一个问题。本研究的目的是评估发表偏倚对老年人渐进抗阻训练(PRT)有效性的系统评价的影响。 研究设计和背景:相关研究通过三个来源确定:电子数据库、专家和手工检索。采用捕获-重捕获、漏斗图的目视检查、两项统计检验和两种针对发表偏倚进行调整的方法来检查系统评价结论的稳健性。结果:所采用的方法给出了大致一致的结果。 Capture-recapture 估计有 3 项 (95% CI [1,15]) 相关研究被遗漏,而 Trim and Fill 则估计有 16 项研究被遗漏。艾格的偏倚检验和漏斗图回归方法都表明存在发表偏倚。选择模型方法表明,观察到的漏斗图不对称可能并不完全是由于发表偏倚造成的。结论:捕获-再捕获是评估发表偏倚的潜在有用方法。需要以模拟研究的形式进行进一步的研究,使用各种场景来调查每种方法接近真实情况的程度。 (C) 2004 Elsevier Inc. 保留所有权利。
Objectives: Publication bias is a problem in systematic reviews of randomized controlled trials. The aim of this study was to assess the influence of publication bias in a systematic review of the effectiveness of Progressive Resistance Training (PRT) in older people.Study Design and Setting: The relevant studies were ascertained from three sources: electronic databases, experts, and handsearching. Capture-recapture, visual inspection of funnel plots, two statistical tests, and two methods that make adjustments for publication bias, were employed to check the robustness of the conclusions of the systematic review.Results: The methods employed gave broadly consistent results. Capture-recapture estimated that 3 (95% CI [1,15]) relevant studies were missed, while Trim and Fill suggested 16 studies had been missed. Both Egger's test for bias and a funnel plot regression approach suggested that publication bias was present. A selection model approach suggested that the funnel plot asymmetry observed may not be entirely due to publication bias.Conclusion: Capture-recapture is a potentially useful method for assessing publication bias. Further research in the form of simulation studies is required, using a variety of scenarios to investigate the extent to which each method approximates the truth. (C) 2004 Elsevier Inc. All rights reserved.