Enzyme-directed positioning of nanoparticles on large DNA templates

Enzyme-directed positioning of nanoparticles on large DNA templates
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DOI:
10.1021/bc700275h
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发表时间:
2008-02-01
影响因子:
4.7
通讯作者:
Reich, Norbert O.
Reich, Norbert O.
中科院分区:
化学2区
文献类型:
--
作者:
Braun, Gary;Diechrierow, Michael;Reich, Norbert O.

文献摘要

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描述了一种使用基于酶的方法以高分辨率将纳米颗粒定位到 DNA 上的方法。这提供了一种将多个纳米粒子(例如 An 和 CdSe)组装到特定位置的便捷途径,并且具有高水平的控制性和可扩展到更复杂组件的能力。原子力显微镜用于分析纳米结构,这对生物传感器、光波导、分子电子学和能量传递研究具有潜在的兴趣。
A method to position nanoparticles onto DNA with high resolution using an enzyme-based approach is described. This provides a convenient route to assemble multiple nanoparticles (e.g., An and CdSe) to specific positions with a high level of control and expandability to more complex assemblies. Atomic force microscopy is used to analyze the nanostructures, which have potential interest for biosensor, optical waveguide, molecular electronics, and energy transfer studies.