Fiber tracking of the frontal aslant tract and subcomponents of the arcuate fasciculus in 5-8-year-olds: Relation to speech and language function
Fiber tracking of the frontal aslant tract and subcomponents of the arcuate fasciculus in 5-8-year-olds: Relation to speech and language function
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DOI：
10.1016/j.bandl.2015.06.006
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发表时间：
2015-10-01
影响因子：
2.5
通讯作者：
Dick, Anthony Steven
中科院分区：
文献类型：
--
作者：
Broce, Iris;Bernal, Byron;Dick, Anthony Steven
长关联皮层纤维通路支持言语和语言网络的发展，但我们对它们在儿童早期是如何发展的还不清楚。我们使用弥散加权成像（DWI）追踪了19名典型的5-8岁儿童的额斜束（FAT）、弓状束（AF）和AF节段（前、长、后），该年龄段的儿童言语和语言功能显著改善。在我们调查的年龄范围内，FAT和右心房的显微结构特性没有显示出与年龄相关的差异，而左心房的各向异性随着年龄的增长而增加。然而，两个脑半球AF的微观结构特性预测了接受性和表达性语言。左侧FAT的长度也预测了接受性语言，这初步表明这条通路对语言发展很重要。这些发现对语言发展模型和更广泛的语言神经生物学模型具有启示意义。(C) 2015爱思唯尔公司版权所有。
Long association cortical fiber pathways support developing networks for speech and language, but we do not have a clear understanding of how they develop in early childhood. Using diffusion-weighted imaging (DWI) we tracked the frontal aslant tract (FAT), arcuate fasciculus (AF), and AF segments (anterior, long, posterior) in 19 typical 5-8-year-olds, an age range in which significant improvement in speech and language function occurs. While the microstructural properties of the FAT and the right AF did not show age-related differences over the age range we investigated, the left AF evidenced increasing fractional anisotropy with age. Microstructural properties of the AF in both hemispheres, however, predicted receptive and expressive language. Length of the left FAT also predicted receptive language, which provides initial suggestion that this pathway is important for language development. These findings have implications for models of language development and for models of the neurobiology of language more broadly. (C) 2015 Elsevier Inc. All rights reserved.