Real-time assessment of alcohol drinking and drug use in opioid-dependent polydrug users.
Real-time assessment of alcohol drinking and drug use in opioid-dependent polydrug users.
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DOI：
10.1097/fbp.0000000000000250
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发表时间：
2016-10
影响因子：
1.6
通讯作者：
Epstein DH
中科院分区：
文献类型：
--
作者：
Preston KL;Jobes ML;Phillips KA;Epstein DH
我们使用生态瞬时评估(EMA)在一个不酗酒的多药吸毒者样本中调查了饮酒、其他药物使用和药物渴求之间的关系。在一项前瞻性纵向队列研究中，114名接受美沙酮维持治疗的海洛因和可卡因使用者在醒着的时候携带手持电子日记，并接受了长达25周的毒品和酒精使用筛查。符合DSM酒精滥用或依赖标准的个人被排除在外。参与者每天对2-5个随机提示做出反应，报告他们的情绪、渴望和活动，并在他们使用或强烈渴望海洛因或可卡因时开始输入。在两种类型的条目中都对饮酒进行了评估。每周三次测量呼气酒精。参与者报告了1.6%的随机提示条目、3.7%的事件应急条目在渴望可卡因和/或海洛因时饮酒、11.6%的事件应急条目在吸食可卡因和/或海洛因时饮酒。饮酒也与更高的渴望等级和研究前的酒精使用有关。动态自我报告比门诊呼气测试检测到更多的饮酒。尽管我们已经从我们的多药使用者样本中筛选出酗酒者，但饮酒与海洛因和可卡因的渴望和实际使用有关。
We investigated relationships between drinking, other drug use, and drug craving, using ecological momentary assessment (EMA), in a sample of polydrug users who were not heavy drinkers. In a prospective longitudinal cohort study, 114 heroin and cocaine users in methadone-maintenance treatment carried handheld electronic diaries during waking hours and were screened for drug and alcohol use for up to 25 weeks. Individuals who met DSM criteria for alcohol abuse or dependence were excluded. Participants responded to 2–5 random prompts per day to report on their moods, cravings, and activities, and initiated entries when they used or acutely craved heroin or cocaine. Drinking alcohol was assessed in both types of entries. Breath alcohol was measured three times weekly. Participants reported drinking alcohol in 1.6% of random-prompt entries, 3.7% of event-contingent entries when craving cocaine and/or heroin, and 11.6% of event-contingent entries when using cocaine and/or heroin. Alcohol drinking was also associated with higher craving ratings and pre-study alcohol use. More drinking was detected by ambulatory self-report than by in-clinic breath testing. Even though we had screened out heavy drinkers from our sample of polydrug users, drinking was associated with heroin and cocaine craving and actual use.