Progestin-primed ovarian stimulation with or without clomiphene citrate supplementation in normal ovulatory women undergoing in vitro fertilization/intracytoplasmic sperm injection: A prospective randomized controlled trial
Progestin-primed ovarian stimulation with or without clomiphene citrate supplementation in normal ovulatory women undergoing in vitro fertilization/intracytoplasmic sperm injection: A prospective randomized controlled trial
复制标题
对接受体外受精/胞浆内单精子注射的正常排卵女性进行孕激素引发的卵巢刺激，并补充或不补充克罗米芬：一项前瞻性随机对照试验
DOI：
10.1111/cen.13532
复制
发表时间：
2018-03-01
影响因子：
3.2
通讯作者：
Kuang, Yanping
中科院分区：
文献类型：
--
作者：
Liu, Yali;Chen, Qiuju;Kuang, Yanping
目的比较孕激素促排卵（PPOS）加或不加克罗米芬（CC）对正常排卵妇女行体外受精（IVF）/卵胞浆内单精子注射（ICSI）的内分泌、周期特征和妊娠结局的影响。在月经周期第3天同时给予醋酸甲羟孕酮（MPA）和人绝经期促性腺激素（hMG）。这些妇女被随机分为两组，有或没有CC补充。
ObjectiveTo compare the endocrinological profiles, cycle characteristics and pregnancy outcomes of progestin-primed ovarian stimulation (PPOS) with or without clomiphene citrate (CC) supplementation in normal ovulatory women undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI).DesignProspective randomized controlled study.Patient(s)A total of 320 infertile women undergoing IVF/ICSI. Medroxyprogesterone acetate (MPA) and human menopausal gonadotropin (hMG) were simultaneously administered on menstrual cycle day 3. The women were randomized into 2 equal groups with or without CC supplementation.MeasuresThe primary outcome measure was the percentage of women with profound pituitary suppression (luteinizing hormone [LH]