Prevalence of Panton-Valentine leukocidin genes in methicillin-resistant Staphylococcus aureus isolates phenotypically consistent with community-acquired MRSA, 1999-2007, Vienna General Hospital
Prevalence of Panton-Valentine leukocidin genes in methicillin-resistant Staphylococcus aureus isolates phenotypically consistent with community-acquired MRSA, 1999-2007, Vienna General Hospital
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DOI：
10.1007/s10096-009-0721-9
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发表时间：
2009-08-01
影响因子：
4.5
通讯作者：
Assadian, O.
中科院分区：
文献类型：
--
作者：
Bauer, C. C.;Apfalter, P.;Assadian, O.
本研究的目的是调查耐甲氧西林金黄色葡萄球菌（MRSA）菌株的抗生素耐药性仅限于β-内酰胺类抗生素和可变耐夫西地酸的Panton-Valentine杀白细胞素（PVL）基因的存在。我们的数据显示，在我院MRSA分离株中很少发现选择性耐药模式，但似乎这种表型与典型的社区获得性（ca）MRSA一致，表明PVL阳性MRSA。
The purpose of this study was to investigate methicillin-resistant Staphylococcus aureus (MRSA) isolates with antibiotic resistance restricted to beta-lactam antibiotics and variable resistance to fusidic acid for the presence of Panton-Valentine leukocidin (PVL) genes. Our data show that the selected resistance pattern is found rarely among MRSA isolates in our hospital, but it appears that this phenotype consistent with typical community-acquired (ca) MRSA is indicative of PVL-positive MRSA.