Employment status is associated with both physical and mental health quality of life in people living with HIV

Employment status is associated with both physical and mental health quality of life in people living with HIV
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DOI:
10.1080/09540121.2010.507952
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发表时间:
2011-01-01
影响因子:
1.7
通讯作者:
Rourke, Sean B.
Rourke, Sean B.
中科院分区:
医学4区
文献类型:
--
作者:
Rueda, Sergio;Raboud, Janet;Rourke, Sean B.

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探讨HIV感染者/AIDS患者的就业状况与健康相关生活质量的关系。共有361名参与者提供了正在进行的队列研究的背景下,检查神经行为功能的自然史及其对HRQOL的影响的基线数据。我们进行测试并收集实验室数据,以确定人口统计学状况,HIV疾病标志物,心理社会症状负担,神经认知功能和HRQOL(MOS-HIV)。我们进行了回归分析,以评估就业状况对生活质量(QOL)的身心健康组成部分的贡献。多变量分析表明,在控制了潜在的混杂因素后,就业状况与更好的身心健康生活质量密切相关。然而,我们发现,就业状况对身体健康的影响大于心理健康QOL [身体健康(β = 6.8,95% CI 4.6至9.1)和心理健康QOL(β = 3.3,95% CI 0.93至5.7)]。就业对身体健康QOL的影响强于种族,社会支持或有艾滋病诊断,并与许多艾滋病毒相关症状的观察。这项横断面研究表明,可能有获得或保持就业相关的身体和心理健康的好处,或更有可能的选择和因果关系的机制,包括一个相互干扰和加强的过程。
To evaluate the relationship between employment status and health-related quality of life (HRQOL) in HIV/AIDS. A total of 361 participants provided baseline data in the context of an ongoing cohort study examining the natural history of neurobehavioral functioning and its effects on HRQOL. We administered tests and collected laboratory data to determine demographic status, HIV disease markers, psychosocial symptom burden, neurocognitive function and HRQOL (MOS-HIV). We performed regression analyses to evaluate the contribution of employment status to the physical and mental health components of quality of life (QOL). Multivariate analyses showed that employment status was strongly related to better physical and mental health QOL after controlling for potential confounders. We found, however, that employment status had a greater impact on physical health than mental health QOL [physical health (beta = 6.8, 95% CI 4.6 to 9.1) and mental health QOL (beta = 3.3, 95% CI 0.93 to 5.7)]. The effect of employment for physical health QOL was stronger than that observed for ethnicity, social support, or having an AIDS diagnosis and was comparable to that observed with having many HIV-related symptoms. This cross-sectional study suggests that there may be physical and mental health benefits associated with obtaining or keeping employment, or more likely that both selection and causation mechanisms comprise an interactional and reinforcing process.