Necessity of introducing particle size distribution of hand-adhered soil on the estimation of oral exposure to metals in soil: Comparison with the traditional method
Necessity of introducing particle size distribution of hand-adhered soil on the estimation of oral exposure to metals in soil: Comparison with the traditional method
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DOI：
10.1016/j.jhazmat.2023.130891
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发表时间：
2023-02-08
影响因子：
13.6
通讯作者：
Duan，Xiaoli
中科院分区：
文献类型：
--
作者：
Wang，Beibei;Gao，Fei;Duan，Xiaoli
本研究旨在系统研究土壤颗粒大小与儿童暴露可能性、重金属浓度、重金属生物可利用性的关系。招募了50名3-8岁的儿童，用于收集手粘土壤、环境土壤和血液样品。分析了手粘土的质量随粒径的分布。在此基础上，将环境土壤样品分为5个组分，研究了土壤粒径对有毒金属全量和生物可累积性的影响。在此基础上，建立了基于手粘土壤粒径分布的土壤经口暴露模型，并与典型的传统方法进行了比较。我们发现，较细的颗粒优先粘附到手。最高的金属浓度和bioaccessibility发生在最好的部分，值随粒径的增加而降低。使用改进模型的暴露水平是传统方法的2.0-3.4倍。此外，与传统的土壤铅暴露水平相比，改进模型计算的铅暴露水平与血铅暴露水平的相关性更强、更显著。基于手粘土壤构建的精细化暴露情景更能准确反映真实的暴露水平和个体差异。
This study aimed to systematically investigate the relationship between children exposure possibility, metal concentration, metal bioaccessibility and soil particle size. fifty Children aged 3–8 years were recruited for the collection of hand-adhered soil, environmental soil, and blood samples. The mass distribution of hand-adhered soil with particle size were analyzed. Based on it, environmental soil samples were divided into five fractions to evaluate the effect of soil particle size on the total contents and bioaccessibilities of toxic metals. Then, a refined soil oral exposure model based on the particle size distribution of hand-adhered soil was established, and the estimation was compared with the typical traditional method. We found that finer particles were preferentially adhered to hand. The highest metal concentrations and bioaccessibilities occurred in the finest fraction, with values decreasing with increasing particle size. The exposure levels using the refined model were 2.0–3.4 times higher than those with the traditional method. In addition, Pb exposure level calculated using the refined model exhibited stronger and more significant correlation with blood Pb than those of the traditional soil. The construction of a refined exposure scenario based on hand-adhered soil could more exactly reflect the real exposure level and the difference among individuals.