VALUE OF URINARY ERYTHROCYTE MORPHOLOGY IN ASSESSMENT OF SYMPTOMLESS MICROHAEMATURIA

VALUE OF URINARY ERYTHROCYTE MORPHOLOGY IN ASSESSMENT OF SYMPTOMLESS MICROHAEMATURIA
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尿红细胞形态学在无症状微血尿评估中的价值

DOI:
10.1016/s0140-6736(89)91919-3
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发表时间:
1989
期刊:
The Lancet
影响因子:
--
通讯作者:
M. Maier
M. Maier
中科院分区:
--
文献类型:
--
作者:
P. Schramek;M. Georgopoulos;F. Schuster;P. Porpaczy;M. Maier

文献摘要

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为了评估尿液红细胞形态显微镜分析作为孤立性无症状微血尿患者调查的第一步的价值,我们连续对316例患者进行了分组,分组依据是他们排出的红细胞是正常的还是混合的,还是只有畸形的。前一组进行了充分的调查,123例患者中有85%发现泌尿系统疾病。192例尿液中红细胞完全畸形而肾功能正常(良性肾微血尿)的患者每年进行尿红细胞形态和肾功能的随访检查,当发现变化时进行侵入性诊断。132名患者中只有2名随访至少2年出现了新的疾病;这在一次年度考试中很容易被发现。因此,尿红细胞形态的显微分析是鉴别无症状微血尿患者的有效方法,需要进行具体的诊断调查。
To assess the value of microscopic analysis of urinary erythrocyte morphology as the initial step in the investigation of patients with isolated symptomless microhaematuria, 316 consecutive patients were grouped according to whether they excreted eumorphic or mixed forms of erythrocytes or only dysmorphic forms. The former group was investigated fully, and urological disease was found in 85% of 123 patients. The 192 patients with exclusively dysmorphic erythrocytes in their urine and normal renal function (benign renal microhaematuria) were assigned to annual follow-up examinations of urinary red cell morphology and renal function, and subjected to invasive diagnostic procedures when a change was noted. In only 2 of the 132 patients followed up for at least 2 years did a new disease develop; this was easily identified at one of the annual examinations. Microscopic analysis of urinary erythrocyte morphology is therefore an effective method for identifying patients with symptomless microhaematuria needing specific diagnostic investigation.