SEASONALITY IN SEVERITY OF DEPRESSION - RELATIONSHIPS TO SUICIDE AND HOMICIDE OCCURRENCE
SEASONALITY IN SEVERITY OF DEPRESSION - RELATIONSHIPS TO SUICIDE AND HOMICIDE OCCURRENCE
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DOI：
10.1111/j.1600-0447.1993.tb03431.x
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发表时间：
1993-09-01
影响因子：
6.7
通讯作者：
DEMEYER, F
中科院分区：
文献类型：
--
作者：
MAES, M;MELTZER, HY;DEMEYER, F
以前的一些研究报告了抑郁综合征的发生有季节性或月度性变化。本研究旨在探讨抑郁症严重程度的季节性。为此，作者测量了1983年11月至1985年4月期间连续入院的104名抑郁症患者的Zung抑郁(ZD)和焦虑(ZA)量表得分。采用单时间序列的谱分析方法对数据进行分析。ZD评分周平均值的41.9%可以用51周(一年一次)和7周两个显著节律来解释。ZD评分的峰值出现在4-5月，最低出现在8-9月。高达30.8%的ZA分数周平均值的变化可以用一年一次的节律来解释。我们的研究结果表明，抑郁症患者的病情严重程度具有真正的季节性。在比利时，每周平均病情严重程度与自杀(正)和凶杀(负)的发生年表有显著的相关性。
Some previous studies have reported seasonal or monthly variations in the occurrence of depressive syndromes. The present study was carried out in order to investigate seasonality in severity of depression. Toward this end, the authors measured the Zung Self-Rating Depression (ZD) and Anxiety (ZA) Scales scores in 104 consecutively admitted depressed patients between November 1983 and April 1985. The data were analyzed by means of spectral analysis of a single time series. Up to 41.9% of the variance in the weekly average of the ZD scores could be explained by two significant rhythms of 51 (circannual) and 7 weeks. Peaks in ZD scores were observed in April-May, with lows occurring in August-September. Up to 30.8% of the variance in the weekly average of ZA scores was explained by a circannual rhythm. Our results show that there is a true seasonality in the severity of illness of depressed subjects. There were significant correlations between the weekly average in severity of illness and the chronograms of suicide (positively) and homicide (negatively) occurrence in Belgium.