Many quantitative trait loci for feather growth in an F(2) broiler × layer cross collocate with body weight loci.
Many quantitative trait loci for feather growth in an F(2) broiler × layer cross collocate with body weight loci.
复制标题
F(2) 肉鸡与蛋鸡杂交中羽毛生长的许多数量性状基因座与体重基因座配对。
DOI：
10.1080/00071668.2012.668613
复制
发表时间：
2012
影响因子：
2
通讯作者：
Hocking PM
中科院分区：
文献类型：
--
作者：
Hocking PM
1.对467个肉鸡杂交F_2代进行全基因组扫描，以确定影响尾羽、翅羽、背羽生长速度和胸羽束宽的数量性状基因座(QTL)。各性状间的相关系数在0.36~0.61之间。雄性的尾羽和翅膀比雌性的长，背部的羽短。女性胸毛束宽度大于男性。QTL效应一般为加性效应，占品种性别平均羽长的11%~45%，占胸毛束宽的100%。两个品系均遗传了正负向等位基因，调整体重后蛋鸡等位基因大于肉鸡。共检测到4个基因组显着QTL和4个暗示QTL。在3周龄或6周龄时，有5个QTL位于与体重QTL相似的区域。以3周龄体重为协变量的模型分析，确定了5个基因组显著QTL和6个提示性QTL，其中只有2个与体重QTL一致。在未经调整的分析中，在GGA1上的类似位置上发现了一个位于148 cM处的羽长QTL。结果表明，羽毛生长速度在很大程度上受体重QTL控制，也存在与羽毛生长相关的QTL。
1. A genome-wide scan of 467 F2progeny of a broilerxlayer cross was conducted to identify quantitative trait loci (QTL) affecting the rate of growth of the tail, wing and back feathers, and the width of the breast feather tract, at three weeks of age.2. Correlations between the traits ranged from 0·36 to 0·61. Males had longer tail and wing feathers and shorter back feathers than females. Breast feather tract width was greater in females than males.3. QTL effects were generally additive and accounted for 11 to 45% of sex average feather lengths of the breeds, and 100% of the breast feather tract width. Positive and negative alleles were inherited from both lines, whereas the layer allele was larger than the broiler allele after adjusting for body weight.4. A total of 4 genome-significant and 4 suggestive QTL were detected. At three or 6 weeks of age, 5 of the QTL were located in similar regions as QTL for body weight.5. Analysis of a model with body weight at three weeks as a covariate identified 5 genome significant and 6 suggestive QTL, of which only two were coincident with body weight QTL. One QTL for feather length at 148 cM on GGA1 was identified at a similar location in the unadjusted analysis.6. The results suggest that the rate of feather growth is largely controlled by body weight QTL, and that QTL specific for feather growth also exist.