Villitis of known origin: Varicella and toxoplasma

Villitis of known origin: Varicella and toxoplasma
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DOI:
10.1053/plac.1999.0405
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发表时间:
1999-07-01
期刊:
影响因子:
3.8
通讯作者:
Key, T
Key, T
中科院分区:
医学3区
文献类型:
--
作者:
Benirschke, K;Coen, R;Key, T

文献摘要

被引文献

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慢性绒毛炎是人类胎盘的常见疾病。在某些情况下,可以证明感染原因,如巨细胞病毒和风疹病毒感染。大多数情况下,它是未知的病因,所谓的VUE(病因不明的绒毛炎)。我们描述了两种情况下,识别特定的传染性病原体,每个证明以前未报告的结果,即持续性水痘抗原在绒毛中的情况下1,和弓形虫囊肿的存在下,在沃顿氏果冻的情况下2。病原体的鉴定,水痘病毒和弓形虫,在胎盘的常规研究中很容易被忽视,因为临床怀疑是可能的。(C)小行星1999 W. B。Saunders Company Ltd
Chronic villitis is a common condition in human placentae. In some cases an infectious cause can be demonstrated, such as infection with cytomegalovirus and rubella virus. Most often it is of unknown aetiology, the so-called VUE (villitis of unknown aetiology). We describe two cases with identification of specific infectious agents, each demonstrating previously unreported findings, i.e. persistent varicella antigen in the villi in case 1, and presence of toxoplasma cysts in Wharton's jelly in case 2. The identification of the pathogens, varicella virus and toxoplasma, would easily have been overlooked in routine study of the placenta and were possible because of clinical suspicion. (C) 1999 W. B. Saunders Company Ltd.