Ovariectomy in grasshoppers increases somatic storage, but proportional allocation of ingested nutrients to somatic tissues is unchanged.
Ovariectomy in grasshoppers increases somatic storage, but proportional allocation of ingested nutrients to somatic tissues is unchanged.
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DOI：
10.1111/j.1474-9726.2011.00737.x
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发表时间：
2011-12
期刊：
影响因子：
7.8
通讯作者：
Hatle JD
中科院分区：
文献类型：
--
作者：
Judd ET;Wessels FJ;Drewry MD;Grove M;Wright K;Hahn DA;Hatle JD
减少繁殖增加了几种动物的储存和寿命。一次性胞体假说认为，这种寿命延长是通过将摄取的营养从生殖转移到胞体来实现的。大量间接证据支持这一假设，但没有对长寿动物的营养进行直接跟踪，因为它们的繁殖力直接下降。在这里，我们使用稳定的同位素来跟踪长寿的去卵巢蝗虫从摄取到身体器官的碳和氮。卵巢切除后，体细胞储存的三个估计值(即血淋巴储存蛋白的数量、股骨肌肉碳水化合物的数量和脂肪体的大小)都翻了一番。与之形成鲜明对比的是，卵巢切除并没有增加这些组织中由最近摄入的食物制成的比例。换句话说，卵巢切除对这些躯体组织相对分配的生理基础没有影响。因此，在整个组织储存的水平上，这些结果与繁殖和寿命之间的权衡是一致的。相比之下，我们的稳定同位素数据与这样的预测不一致，即去卵巢的女性体内储存的增加是由于摄入的营养分配发生了生理变化。
Reduced reproduction increases storage and extends lifespan in several animal species. The disposable soma hypothesis suggests this life extension occurs by shifting allocation of ingested nutrients from reproduction to the soma. A great deal of circumstantial evidence supports this hypothesis, but no direct tracking of nutrients has been performed in animals that are long‐lived because of direct reduction in reproduction. Here, we use the stable isotopes to track carbon and nitrogen from ingestion to somatic organs in long‐lived, ovariectomized grasshoppers. Three estimates of somatic storage (viz., quantity of hemolymph storage proteins, amount of femur muscle carbohydrates, and size of the fat body) all doubled upon ovariectomy. In stark contrast, ovariectomy did not increase the proportion of these tissues that were made from recently ingested foods. In other words, the physiology underlying relative allocation to these somatic tissues was not affected by ovariectomy. Thus, at the level of whole tissue storage, these results are consistent with a trade‐off between reproduction and longevity. In contrast, our stable isotope data are inconsistent with the prediction that enhanced storage in ovariectomized females results from a physiological shift in allocation of ingested nutrients.