CONTROL OF SLEEP STATES IN RAT BY SHORT LIGHT-DARK CYCLES
CONTROL OF SLEEP STATES IN RAT BY SHORT LIGHT-DARK CYCLES
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DOI：
10.1016/0006-8993(75)90209-7
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发表时间：
1975-01-01
期刊：
影响因子：
2.9
通讯作者：
WASER, PG
中科院分区：
文献类型：
--
作者：
BORBELY, AA;HUSTON, JP;WASER, PG
本文研究了60-60 min光暗循环对大鼠睡眠、摄食、饮水和运动活动的影响。光抑制觉醒、完成行为和运动活动，而增强睡眠。这些效应取决于光的强度。慢波睡眠（SS）的百分比增加的第一个15分钟内的光周期，并在30分钟内达到一个平台。SS在黑暗中的减少表现出类似的时间过程。异相睡眠（PS）的百分比开始增加，只有15分钟后，开始的光和黑暗的第一个15分钟期间继续上升。所有参数均表现出自由运行的昼夜节律。LD诱导的SS的变化是最大的在昼夜节律的阶段，在该动物是活跃的。PS的变化在非活动时相最大，并随光照的开始或结束而变化。光照变化的最直接影响是施加在睡眠的慢波成分上。讨论了解释两种睡眠状态之间暂时分离的假设。
The effects of 60-60 min light-dark (LD) cycles on sleep, feeding, drinking and motor activity were investigated in the rat. Waking, consummatory behavior and motor activity were inhibited by light, while sleep was enhanced. The effects were dependent on the intensity of light. The percentage of slow wave sleep (SS) increased within the first 15 min of the light period and reached a plateau within 30 min. The reduction of SS during darkness showed a similar time-course. The percentage of paradoxical sleep (PS) started to increase only 15 min after the onset of light and continued to rise during the first 15 min of darkness. All parameters exhibited a free-running circadian rhythm. The LD-induced changes of SS were largest during the circadian phase in which the animal was active. The changes of PS which succeeded the onset or offset of light, were largest in the inactive circadian phase. The most immediate influence of changes in illumination is exerted on the slow wave component of sleep. Hypotheses to account for the temporary dissociation between the two sleep states are discussed.