Resource competition and social conflict in experimental populations of yeast
Resource competition and social conflict in experimental populations of yeast
复制标题
DOI：
10.1038/nature04624
复制
发表时间：
2006-05-25
期刊：
影响因子：
64.8
通讯作者：
Gudelj, I
中科院分区：
文献类型：
--
作者：
MacLean, RC;Gudelj, I
理解促进合作维持的条件是进化生物学中的一个经典问题（1-5）。“公地悲剧”抓住了这一困境的本质：一群以合作方式开发资源的个人如何抵御“骗子”的入侵，这些骗子自私地使用公共资源，以牺牲群体的利益来最大化他们的个人再生产（7,8）？在这里，我们通过具有不同葡萄糖代谢途径的等基因作弊菌株和合作菌株之间的实验竞争来研究这种冲突(9)，并使用微生物生物化学的数学模型（10）。我们表明共存和竞争排斥都是这种冲突的可能结果，这取决于环境的时空结构。这两种结果都是由代谢中间体介导的资源转化为后代的速度和效率之间的权衡所驱动的。
Understanding the conditions that promote the maintenance of cooperation is a classic problem in evolutionary biology(1-5). The essence of this dilemma is captured by the 'tragedy of the commons' 6: how can a group of individuals that exploit resources in a cooperative manner resist invasion by 'cheaters' who selfishly use common resources to maximize their individual reproduction at the expense of the group(7,8)? Here, we investigate this conflict through experimental competitions between isogenic cheater and cooperator strains of yeast with alternative pathways of glucose metabolism(9), and by using mathematical models of microbial biochemistry(10). We show that both coexistence and competitive exclusion are possible outcomes of this conflict, depending on the spatial and temporal structure of the environment. Both of these outcomes are driven by trade-offs between the rate and efficiency of conversion of resources into offspring that are mediated by metabolic intermediates.