Mortality from cancer in relation to smoking: 50 years observations on British doctors.
Mortality from cancer in relation to smoking: 50 years observations on British doctors.
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DOI：
10.1038/sj.bjc.6602359
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发表时间：
2005-02-14
影响因子：
8.8
通讯作者：
中科院分区：
文献类型：
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作者：
共有34439名英国男性医生在1951年11月报告了他们的吸烟习惯，他们被跟踪，定期更新他们的习惯变化，直到死亡，移民，审查。或2001年11月。在国际癌症研究机构审查的30种男性癌症中，获得了28种癌症的死亡率信息（另外两种没有死亡记录）。总的来说，在该机构归类为可能由吸烟引起的13种男性中，有11种与吸烟密切相关，而另外两种仅导致少数死亡的调查结果表明，它们可能是。在13种男性类型中，该机构只发现了稀疏或不一致的数据，而我们有数据，只有两种似乎可能相关（一种是正相关的，一种是负相关的），638例死亡的总和显然与吸烟无关。在FDA认为与吸烟的关系可能是由于偏倚或混杂因素所致的两种类型中，一种（前列腺癌）的结果倾向于支持吸烟无关的观点，另一种（结直肠癌）的结果显示与吸烟的关系较弱，这（在一个小子集中）不能归因于与饮酒的混杂。
A total of 34 439 male British doctors, who reported their smoking habits in November 1951, were followed, with periodic up date of changes in their habits, until death, emigration, censoring. or November 2001. Information was obtained about their mortality from 28 of the 30 types of cancer in men reviewed by the International Agency for Research on Cancer (no death was recorded from the other two). In all, 11 of the 13 types in men that the Agency classed as liable to be caused by smoking were significantly related to smoking and the findings for the other two, which caused only few deaths, suggested they might be. Of the 13 types in men for which the Agency found only sparse or inconsistent data and for which we had data, only two appeared to be possibly related (one positively, one negatively), and the 638 deaths for the summed group were clearly unrelated to smoking. Of the two types for which the Agency thought that the relationship with smoking might be due to bias or confounding, the findings for one (prostate cancer) tended to support the belief that smoking was unrelated, and those for the other (colorectal cancer) showed a weak relationship with smoking, which (in a small subset) could not be attributed to confounding with the consumption of alcohol.
影响因子：
--
作者：
DOLL, R;PETO, R;SUTHERLAND, I
通讯作者：
SUTHERLAND, I
影响因子：
105.7
作者：
Doll, R;Peto, R;Sutherland, I
通讯作者：
Sutherland, I
影响因子：
5.1
作者：
Corrao, G;Bagnardi, V;La Vecchia, C
通讯作者：
La Vecchia, C