A Randomized Clinical Trial Comparing Contact Lens With Intraocular Lens Correction of Monocular Aphakia During Infancy Grating Acuity and Adverse Events at Age 1 Year
A Randomized Clinical Trial Comparing Contact Lens With Intraocular Lens Correction of Monocular Aphakia During Infancy Grating Acuity and Adverse Events at Age 1 Year
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DOI：
10.1001/archophthalmol.2010.101
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发表时间：
2010-07-01
影响因子：
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通讯作者：
Ward, Michael
中科院分区：
文献类型：
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作者：
Lambert, Scott R.;Buckley, Edward G.;Ward, Michael
目的：比较接触透镜与初级人工透镜（IOL）纠正单眼无晶状体眼在infanty.Methods的视力结果和不良事件：在一项随机，多中心（12个网站）的临床试验，114名婴儿与单侧先天性白内障被分配到1至6个月的年龄进行白内障手术，无论有或没有初级人工晶状体植入术。在未接受IOL的患者中，使用角膜接触镜矫正无晶状体眼。光栅视力在1岁时由一个蒙面的旅行examinator.Main结果测量：光栅视力在1岁时。结果：中位logMAR视力没有显着差异治疗的眼睛在2组（接触透镜组，0.80; IOL组，0.97; P= 0.19）。人工晶状体组比接触透镜组有更多的患者接受了1次或多次额外的眼内手术（63%比12%; P
Objective: To compare the visual outcomes and adverse events of contact lens with primary intraocular lens (IOL) correction of monocular aphakia during infancy.Methods: In a randomized, multicenter (12 sites) clinical trial, 114 infants with a unilateral congenital cataract were assigned to undergo cataract surgery between 1 to 6 months of age either with or without primary IOL implantation. Contact lenses were used to correct aphakia in patients who did not receive IOLs. Grating visual acuity was tested at 1 year of age by a masked traveling examiner.Main Outcome Measure: Grating visual acuity at 1 year of age.Results: The median logMAR visual acuity was not significantly different between the treated eyes in the 2 groups (contact lens group, 0.80; IOL group, 0.97; P=.19). More patients in the IOL group underwent 1 or more additional intraocular operations than patients in the contact lens group (63% vs 12%; P