Cancer of the heart: epidemiology and management of primary tumors and metastases.
Cancer of the heart: epidemiology and management of primary tumors and metastases.
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DOI：
10.2165/00129784-200303060-00004
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发表时间：
2003-01-01
期刊：
影响因子：
--
通讯作者：
Cusimano, Robert J
中科院分区：
文献类型：
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作者：
Sarjeant, Jennifer M;Butany, Jagdish;Cusimano, Robert J
心脏肿瘤，无论是良性还是恶性，都很罕见，大多数是良性的。最常见的良性肿瘤是心脏粘液瘤。恶性心脏肿瘤通常是肉瘤。心包可能是良性和恶性心脏肿瘤的部位，尽管转移性肿瘤在这里发生的频率远高于原发性肿瘤。良性心脏肿瘤的成功治疗通常通过手术切除来实现。然而，原发性恶性肿瘤的手术不太成功，因为通常不可能完全切除。原发性心脏淋巴瘤可以通过化疗成功治疗。从其他器官转移到心脏的肿瘤的发生率比原发性心脏肿瘤高 100 至 1000 倍。大约五分之一的转移性癌症患者已发现转移性扩散至心脏，其中肺癌是最常见的原发性肿瘤。心脏转移的症状各不相同，取决于病变的部位和范围。治疗方法取决于原发肿瘤的病理学。然而，治疗的目的通常是缓解症状。随着艾滋病的出现，心脏组织中也发现了卡波西肉瘤和高级别B细胞淋巴瘤。本文的目的是综述心脏肿瘤的流行病学、临床表现、病理学和治疗。
Cardiac tumors, benign or malignant, are rare and most are benign. The most common benign tumor is the cardiac myxoma. Malignant cardiac tumors are usually sarcomas. The pericardium can be the site of benign and malignant cardiac tumors, though metastatic tumors occur here far more commonly than do primary tumors. Successful treatment for benign cardiac tumors is usually achieved by surgical resection. Surgery for primary malignant tumors is, however, much less successful as complete resection is usually not possible. Primary cardiac lymphoma may be successfully treated by chemotherapy. Tumors that metastasize to the heart from other organs occur 100- to 1000-fold more commonly than primary cardiac tumors. Metastatic spread to the heart has been identified in approximately one-fifth of all patients who have metastatic cancer with lung carcinoma being the most common primary tumor. Symptoms of cardiac metastases vary, and they depend on the site and extent of the lesions. Treatment varies depending on the pathology of the primary tumor. However, the aim of treatment is usually symptomatic relief. With the advent of AIDS, Kaposi's sarcoma and high grade B cell lymphomas have also been identified in cardiac tissue. The aim of this article is to review the epidemiology, clinical presentation, pathology and treatment of cardiac tumors.