Current distribution image of the rat brain using diffusion weighted magnetic resonance imaging
Current distribution image of the rat brain using diffusion weighted magnetic resonance imaging
复制标题
使用扩散加权磁共振成像的大鼠大脑电流分布图像
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
N. Iriguchi
中科院分区：
文献类型：
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作者：
K. Yamaguchi;M. Sekino;S. Ueno;N. Iriguchi
在这篇文章中，我们报告的表观扩散系数（ADC）的大鼠脑组织的增加，外加电流。获得有和没有施加电流的ADC的减影磁共振成像（MRI）图，以定量评估电流对ADC的影响。组织中的ADC通过平均扩散率（MD）或扩散张量Trace（D）/2的对角元素之和直接估计。各向异性扩散由分数各向异性FA（D）估计。实验结果表明，在电流为4、6、8和10 mA时，膜的分子量分别增加了6%、8%、16%和40%。该机制部分解释为离子通过组织中的细胞外空间的运动。
In this article, we report that the apparent diffusion coefficient (ADC) of rat brain tissue increased by applied external electrical currents. A subtraction magnetic resonance imaging (MRI) map of ADCs with and without applied currents was obtained to quantitatively evaluate the effect of the electrical currents on ADC. The ADC in tissue was directly estimated by the mean diffusivity (MD), or the sum of the diagonal elements of the diffusion tensor Trace(D)/2. Anisotropic diffusion was estimated by fractional anisotropy FA(D). The experimental results show that the MD with applied currents of 4, 6, 8, and 10 mA increased by 6%, 8%, 16%, and 40%, respectively. The mechanism is partially explained by the movement of ions through extracellular space in tissue.