Radioiodination of p-hydroxyphenylisopropyladenosine: development of a new ligand for adenosine receptors.
Radioiodination of p-hydroxyphenylisopropyladenosine: development of a new ligand for adenosine receptors.
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对羟基苯基异丙基腺苷的放射性碘化:开发腺苷受体的新配体。
DOI:
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发表时间:
1982
影响因子:
2.1
通讯作者:
H. Baer
中科院分区:
文献类型:
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作者:
R. Munshi;H. Baer
dl-p-Hydroxyphenylisopropyladenosine has been iodinated with 125I and tested as a ligand of adenosine receptors in membranes from rat brain using a filtration assay. Binding studies using l-[3H]phenylisopropyladenosine as a ligand were carried out in parallel, and the binding of both ligands could be displaced by dl-p-hydroxyphenylisopropyladenosine and l-phenylisopropyladenosine in a similar fashion. These data establish the feasibility of using radioiodinated derivatives of adenosine as ligands of suitable types of adenosine receptors.