Proprioceptive and retinal afference modify postsaccadic ocular drift.
Proprioceptive and retinal afference modify postsaccadic ocular drift.
复制标题
本体感觉和视网膜传入改变眼跳后眼漂移。
DOI：
10.1152/jn.1999.82.2.551
复制
发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Guthrie,BL
中科院分区：
文献类型：
--
作者：
Lewis,RF;Zee,DS;Goldstein,HP;Guthrie,BL
眼球扫视后眼睛的漂移会在视网膜上产生图像的运动(视网膜滑移)，从而降低视力。在这项研究中，我们研究了本体感觉和视网膜传入在抑制单侧眼肌麻痹引起的眼球后漂移中的作用。记录了三只单侧眼外肌无力的恒河猴在本体感觉神经支配瘫痪眼球前后的眼球运动。检查了四种视觉状态下的眼球后漂移：正常眼单眼观察(4-wk周期)；双眼观察(2-wk周期)；双眼用缩小视差棱镜观察(2-wk周期)；以及偏瘫眼睛单眼观察(2-wk周期)。肌肉麻痹在偏瘫眼球扫视后产生垂直漂移，即使在动物不能融合的情况下，这种漂移在双眼观察条件下也被抑制。当动物用缩小视差的棱镜用双眼观察时，两只猴子的偏瘫眼睛的漂移被抑制(使用上斜肌)，但通常在一只动物(使用下直肌肌腱切断术)中增强。当漂移运动增强时，他们减少了眼跳结束时存在的视网膜视差。在弱视状态下，弱视患者的眼球后漂移被抑制，而正常眼则被诱导。在正常视觉状态下去传入后，偏瘫眼球后垂直漂移发生了变化。这种漂移的变化是特殊的，并且可变地影响了偏瘫眼球后眼球后漂移运动的幅度和速度。偏瘫眼的去传入不影响正常眼的眼球后漂移，也不损害眼球后眼球后漂移的视觉调节适应。结果证实了几个关于视觉和本体感觉传入在控制眼球后漂移中的作用的新发现：眼球后漂移的非共轭适应不需要双眼融合；在双眼观看状态下可以诱导缓慢的眼球后漂移运动，这种运动减少了视网膜视差，但同时增加了视网膜滑移；来自眼外肌的本体感觉改变了眼球后漂移，但这些改变并不能帮助最大限度地减少视网膜滑动或纠正眼球跳动幅度的错误；视觉调节的眼球后漂移适应不需要来自弱眼的本体感觉传入。
Drift of the eyes after saccades produces motion of images on the retina (retinal slip) that degrades visual acuity. In this study, we examined the contributions of proprioceptive and retinal afference to the suppression of postsaccadic drift induced by a unilateral ocular muscle paresis. Eye movements were recorded in three rhesus monkeys with a unilateral weakness of one vertical extraocular muscle before and after proprioceptive deafferentation of the paretic eye. Postsaccadic drift was examined in four visual states: monocular viewing with the normal eye (4-wk period); binocular viewing (2-wk period); binocular viewing with a disparity-reducing prism (2-wk period); and monocular viewing with the paretic eye (2-wk period). The muscle paresis produced vertical postsaccadic drift in the paretic eye, and this drift was suppressed in the binocular viewing condition even when the animals could not fuse. When the animals viewed binocularly with a disparity-reducing prism, the drift in the paretic eye was suppressed in two monkeys (with superior oblique pareses) but generally was enhanced in one animal (with a tenotomy of the inferior rectus). When drift movements were enhanced, they reduced the retinal disparity that was present at the end of the saccade. In the paretic-eye–viewing condition, postsaccadic drift was suppressed in the paretic eye and was induced in the normal eye. After deafferentation in the normal-eye–viewing state, there was a change in the vertical postsaccadic drift of the paretic eye. This change in drift was idiosyncratic and variably affected the amplitude and velocity of the postsaccadic drift movements of the paretic eye. Deafferentation of the paretic eye did not affect the postsaccadic drift of the normal eye nor did it impair visually mediated adaptation of postsaccadic drift. The results demonstrate several new findings concerning the roles of visual and proprioceptive afference in the control of postsaccadic drift: disconjugate adaptation of postsaccadic drift does not require binocular fusion; slow, postsaccadic drift movements that reduce retinal disparity but concurrently increase retinal slip can be induced in the binocular viewing state; postsaccadic drift is modified by proprioception from the extraocular muscles, but these modifications do not serve to minimize retinal slip or to correct errors in saccade amplitude; and visually mediated adaptation of postsaccadic drift does not require proprioceptive afference from the paretic eye.