Editorial Comment from Dr Sakamoto to Solitary recurrence of prostate cancer surrounded by seminal vesicle/vas deferens‐like epithelium
Editorial Comment from Dr Sakamoto to Solitary recurrence of prostate cancer surrounded by seminal vesicle/vas deferens‐like epithelium
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坂本博士对精囊/输精管样上皮包围的前列腺癌孤立复发的编辑评论
DOI：
10.1002/iju5.12177
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Sakamoto Shinichi
中科院分区：
文献类型：
--
作者：
Katsuda T;Sato N;Mogushi K;Hase T;Muramatsu M.;Sakamoto Shinichi
Takamori等人报告了一例非常罕见的前列腺癌复发病例，放疗后似乎被精囊/输精管样上皮包围。3根据以往的报道，先天性精囊囊肿畸形可分为三类，如（i）孤立性囊肿，（ii）与上尿路异常相关的囊肿，和（iii）与常染色体显性多囊肾病相关的囊肿。在发育过程中，精囊囊肿在20多岁时出现，并开始性活跃。精囊囊肿通常在5厘米以下，常通过各种症状发现，如尿路感染、不孕、前列腺炎、血尿、血精等。4，5大约60%的患者的精囊囊肿常伴有同侧肾发育不全。其原因可能与远端中肾管发育不良及输尿管出芽发育不良有关，导致肾发育不全。4、5关于异位前列腺，虽然很少见，但过去有几个报道。最常见的部位是膀胱和尿道，其次是精囊、睾丸和附睾。一些报告还指出，在女性的子宫颈和阴道中存在异位前列腺。6异位前列腺的发生机制与正常组织的迁移和错位、慢性炎症引起的化生和胚胎组织残留有关。在目前的病例中，既没有肾发育不全，也没有任何症状消失，因此，在复发出现之前存在精囊囊肿的机会似乎很低。另一种可能性可能与异位前列腺有关，其发展为具有精囊/输精管样上皮的恶性癌症。由于以前的证据有限，我们似乎没有明确的答案。然而，这个病例将为前列腺癌的转移特征带来新的见解。由于转移与精囊样上皮是罕见的，这种情况下的长期预后可能是感兴趣的。
Takamori et al. reported a very rare case of prostate cancer recurrence that seemed to be surrounded by seminal vesicle/vas deferens-like epithelium after radiation therapy. 3 Based on the previous report, congenital cystic anomalies of the seminal vesicle may be classified in to three groups, such as (i) isolated cyst,(ii) cysts associated with upper urinary tract anomalies, and (iii) cysts associated with autosomal dominant polycystic kidney disease. During development, cysts of the seminal vesicle emerge when one is in their 20s and become sexually active. Seminal vesicle cysts are usually below 5 cm, which is often discovered by various symptoms, such as urinary tract infections, infertility, prostatitis, hematuria, and hemospermia. 4, 5 Cyst of the seminal vesicle is often associated with ipsilateral renal agenesis in around 60% of the patients. The reason seems that the development of the seminal vesicle cyst associated with the defect in the development of the distal mesonephric duct and misdeveloped ureteral budding, which results in the renal agenesis. 4, 5 Regarding the ectopic prostate, although it is rare, there were several reports in the past. The most common site seems to be the bladder and urethra, followed by seminal vesicle, testis, and epididymis. Some reports also indicated the presence of ectopic prostate in the cervix and vagina in females. 6 The mechanism for the emergence of ectopic prostate has been related to the migration and misplacement of normal tissue, metaplastic change due to chronic inflammation, and retained embryonic tissue. In the current case, neither renal agenesis nor any symptoms existed.So, the chance of existence of a seminal vesicle cyst before the emergence of recurrence seems to be low. Another possibility may be related to the ectopic prostate that developed to be a malignant cancer with the seminal vesicle/vas deferens-like epithelium. Due to limited previous evidence, we seem to have no clear answer. However, this case will bring about new insights into the metastatic feature of prostate cancer. Since metastasis with seminal vesicle-like epithelium is rare, the long-term prognosis of this case may be of interest.
与同侧肾发育不全和膀胱乳头状癌相关的精囊囊肿
影响因子：
5.9
作者：
M. Gorrea;R. Lorente;J. Roel
通讯作者：
J. Roel
被精囊/输精管样上皮包围的前列腺癌孤立性复发
影响因子：
--
作者：
H. Takamori;T. Kamba;Shinji Sumiyoshi;T. Tsuzuki;S. Kashima;T. Yoshino;Takeshi Sano;Takayuki Goto;A. Sawada;S. Akamatsu;Takashi Kobayashi;Toshinari Yamasaki;T. Mizowaki;O. Ogawa;Takahiro Inoue
通讯作者：
Takahiro Inoue
影响因子：
3.2
作者：
Tan FQ;Xu X;Shen BH;Qin J;Sun K;You Q;Shang DS;Zheng XY
通讯作者：
Zheng XY