Differences in Origin and Outcome of Intra-Abdominal Cysts in Male and Female Fetuses
Differences in Origin and Outcome of Intra-Abdominal Cysts in Male and Female Fetuses
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DOI：
10.1159/000495506
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发表时间：
2019-09-01
影响因子：
2.2
通讯作者：
Cohen-Overbeek, Titia E.
中科院分区：
文献类型：
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作者：
Husen, Marjolein;Schut, Pauline C.;Cohen-Overbeek, Titia E.
目的：探讨一组患有腹腔内囊肿的男性和女性胎儿的起源和结局，以便提供管理建议和改善产前咨询。方法：回顾性分析2002年至2016年超声检查158例胎儿腹腔内囊肿的临床资料。排除脐静脉曲张病例。胎儿，新生儿和母亲的特点，从电子病人档案检索。结果如下：在女性胎儿（n = 114）中，与男性胎儿（n = 44）相比，腹腔内囊肿在较晚的胎龄被诊断（中位数32.0 vs. 21.5周，p < 0.001）。女性胎儿的最大产前囊肿直径较大（中位数35与17 mm，p < 0.001）。与男性（n = 15，34.1%）相比，女性（n = 15，13.2%）的相关异常发生率较低。在女性（n = 114）中，大多数囊肿起源于卵巢（n = 81，71.1%）。30例（26.3%）女性新生儿和15例（34.1%）男性新生儿接受了手术（p = 0.33）。肛门直肠畸形存在于6例，往往没有意识到产前。结论：男女胎儿腹腔内囊肿起源的差异，导致产前表现和产后结果的差异，应考虑到产前咨询在一个多学科的团队。胎儿肛周肌群的评估是指。
Objective: To investigate the origin and outcome in a cohort of male and female fetuses with intra-abdominal cysts, in order to provide recommendations on management and to improve prenatal counselling. Methods: From 2002 to 2016, intra-abdominal cysts were detected by ultrasound in 158 fetuses. Cases with an umbilical vein varix were excluded. Fetal, neonatal, and maternal characteristics were retrieved from electronic patient files. Results: In female fetuses (n = 114), intra-abdominal cysts were diagnosed at a later gestational age compared with male fetuses (n = 44) (median 32.0 vs. 21.5 weeks, p < 0.001). The maximum prenatal cyst diameter was larger in female fetuses (median 35 vs. 17 mm, p < 0.001). Associated anomalies were less frequent in females (n = 15, 13.2%) compared with males (n = 15, 34.1%). In females (n = 114), most cysts were of ovarian origin (n = 81, 71.1%). Surgery was performed in 30 (26.3%) female and 15 (34.1%) male neonates (p = 0.33). Anorectal malformations were present in 6 cases and often not recognized prenatally. Conclusions: The differences in the origin of intra-abdominal cysts between male and female fetuses, resulting in differences in prenatal presentation and postnatal outcome should be taken into account in prenatal counseling within a multidisciplinary team. Evaluation of the fetal perianal muscular complex is indicated.