Relation between estimates of cornstarch digestibility by the Englyst in vitro method and glycemic response, subjective appetite, and short-term food intake in young men
Relation between estimates of cornstarch digestibility by the Englyst in vitro method and glycemic response, subjective appetite, and short-term food intake in young men
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DOI：
10.3945/ajcn.2009.28443
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发表时间：
2010-04-01
影响因子：
7.1
通讯作者：
Finocchiaro, E. Terry
中科院分区：
文献类型：
--
作者：
Anderson, G. Harvey;Cho, Clara E.;Finocchiaro, E. Terry
背景：淀粉组成和消化速度是血糖浓度和食物摄入量(FI)的决定因素。目的：我们的目的是描述体外英格利斯特方法估计的淀粉消化率与其对青年男性血糖浓度、主观食欲和FI的影响之间的关系。设计：受试者在1-wk间隔内饮用5份含有50g麦芽糊精、全谷物、高直链淀粉、普通玉米淀粉或不添加淀粉的汤。分别在30min(实验1)和120min(实验2)后测量自由FI，这分别是估计的快速消化淀粉(RDS)和缓慢消化淀粉(RDS)的消化时间。结果：在30min时，麦芽糊精只降低FI[86%RDS，12%抗性淀粉(RS)；P<；0.0001]，但在120min时，全麦(24%RDS，66%RS)、高直链淀粉玉米(40%RDS，48%RS)和普通玉米(27%RDS，39%RS)使FI降低(P<；0.05)。麦芽糊精治疗后30min和120min的餐前血糖浓度分别最高和最低(P<；0.0001)。餐后30min，所有淀粉处理组的血糖曲线下面积均低于对照组(P<；0.05)，但120min时，只有常规玉米淀粉处理组的血糖曲线下面积低于常规处理组(P<；0.05)。所有处理组的餐前食欲均有下降(P<；0.05)。结论：采用Engyst法对淀粉消化率的体外估测可以预测不同淀粉组分对年轻男性餐后30分钟和120分钟的血糖浓度和FI的影响。这项试验在Clinicaltrials.gov上注册为NCT00980941(实验1)和NCT00988689(实验2)。
Background: Starch composition and rate of digestion are determinants of blood glucose concentrations and food intake (FI).Objective: Our objective was to describe relations between estimates of digestibility of starches by the in vitro Englyst method and their effect on blood glucose concentrations, subjective appetite, and FI in young men.Design: Subjects consumed 5 soups containing 50 g maltodextrin, whole-grain, high-amylose, regular cornstarch, or no added starch at 1-wk intervals. Ad libitum FI was measured at 30 min (experiment 1) or 120 min (experiment 2) later, which were the estimated times of digestion of a rapidly digestible starch (RDS) and slowly digestible starch, respectively. Blood glucose concentrations and appetite were measured pre- and postmeal.Results: At 30 min, FI was reduced by maltodextrin only [86% RDS, 12% resistant starch (RS); P < 0.05], but at 120 min FI was reduced by whole-grain (24% RDS, 66% RS), high-amylose corn (40% RDS, 48% RS), and regular corn (27% RDS, 39% RS) (P < 0.0001). The premeal blood glucose concentration at 30 and 120 min was highest and lowest after maltodextrin treatment, respectively (P < 0.0001). After the meal, the blood glucose area under the curve at 30 min was lower after all starch treatments (P < 0.05), but at 120 min the blood glucose area under the curve was lower only after the regular cornstarch treatment (P < 0.05). Pre-meal appetite decreased by all treatments (P < 0.05).Conclusion: The in vitro estimates of starch digestibility by the Englyst method predicted the effects of starch composition on blood glucose concentrations and FI in young men 30 and 120 min after consumption. This trial was registered at clinicaltrials.gov as NCT00980941 for experiment 1 and NCT00988689 for experiment 2. Am J Clin Nutr 2010; 91: 932-9.