Transcatheter Arterial Embolization of Normal Livers and Experimental Hepatic Tumours in the Rat
Transcatheter Arterial Embolization of Normal Livers and Experimental Hepatic Tumours in the Rat
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大鼠正常肝脏和实验性肝肿瘤的经导管动脉栓塞
DOI：
10.1177/028418517701800605
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发表时间：
1977
期刊：
影响因子：
--
通讯作者：
Sjögren Ho
中科院分区：
文献类型：
--
作者：
L. Ekelund;L. Stigsson;Nils Jonsson;Sjögren Ho
用99.3%明胶海绵对正常大鼠进行肝动脉栓塞。通过重复血管造影可以证明，大多数大鼠的动脉闭塞持续至少1至8天。这些正常肝脏的显微镜检查没有发现肝实质损伤的证据。在栓塞后血管造影术在一组大鼠实验性肝肿瘤，可以证明，动脉供应这些肿瘤暂时完全停止。显微镜检查显示这些肿瘤中的一些广泛坏死。最后，未来的临床应用，这种程序作为一种替代肝动脉结扎进行了讨论。
Transcatheter hepatic arterial embolization with Spongostan (99.3% gelatin) was performed in a group of normal rats. By repeat angiography could be demonstrated that arterial occlusions lasted for at least 1 to 8 days in most rats. Microscopy of these normal livers gave no evidence of parenchymatous liver injury. At postembolization angiography in a group of rats with experimental liver tumours it could be demonstrated that arterial supply of these tumours was temporarily completely arrested. Microscopy of some of these neoplasms revealed extensive necroses. The eventual future clinical applications of this procedure as an alternative to hepatic artery ligation is discussed.