[Comparative investigations (computed tomography, X-ray diagnostics, scintigraphy) for the detection of radiation-induced alterations of the lung (author's transl)].
[Comparative investigations (computed tomography, X-ray diagnostics, scintigraphy) for the detection of radiation-induced alterations of the lung (author's transl)].
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[检测辐射引起的肺部变化的比较研究（计算机断层扫描、X 射线诊断、闪烁扫描）（作者翻译）]。
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
W. Hofmann
中科院分区：
文献类型：
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作者：
H. Hermann;E. Wetzel;M. Heller;W. Hofmann
本文观察了24只家兔左肺照射前、中、后肺实质的放射性改变。12只动物接受表面剂量50戈伊，另一半接受40戈伊，相当于病灶剂量分别为47.5 Gy。肺中部剂量戈伊38 Gy，每周分次10戈伊。通过肺动脉造影（99 mTc-MAA），可以在93%的实验动物中证明辐射诱导的灌注阻塞，只有37%的放射性肺栓塞可以通过计算机断层扫描或胸部X线照片检测到。在70%的实验动物中，放射治疗期间已经可以检测到放射性造影改变，计算机断层扫描或X线检查可见的改变出现得更晚。在这里，计算机断层扫描允许比X射线诊断更早地识别吸收的差异。
Radiation-induced alterations of the parenchyma of the lung were investigated in 24 rabbits before, during and after irradiation of the left lung. Of the experimental animals 12 received a surface dose of 50 Gy, the other half 40 Gy, equivalent to a focal dose of 47.5 resp. 38 Gy in the middle of the lung, with a fractionation of 10 Gy per week. By means of lung-scintigraphy (99mTc-MAA) radiation-induced obstructions to perfusion could be demonstrated in 93% of the experimental animals, only in 37% the detection of radiopneumonia was possible by computed tomography or by a roentgenogram of the thorax. In 70% of the experimental animals scintigraphic alterations could be detected already during radiotherapy, the alterations visible by computed tomography or roentgenology appeared much later. Here computed tomography allowed an earlier identification of differences in absorption than X-ray diagnostics.