Brucellosis Vaccines: An Overview
Brucellosis Vaccines: An Overview
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布鲁氏菌病疫苗：概述
DOI：
10.5772/38812
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发表时间：
2012
影响因子：
0.4
通讯作者：
Ebrahimpour Soheil
中科院分区：
文献类型：
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作者：
Hasanjani Roushan Mohammad Reza;Kazemi Sohrab;F. Fatemeh;Ebrahimpour Soheil
目的：布鲁氏菌病是一种重要的人畜共患传染病，
50万人的病例，它发生在动物像野生和活的股票越来越多。绵羊，
牛和山羊是列出的动物样本。这种疾病在人类的症状包括：
波状热、背痛、昏厥、脊椎炎、关节炎和睾丸炎。这种感染会导致流产，
牲畜，这一点是重要的经济损失之一。牛奶产量的减少是另一个原因
这个病也有问题。
材料与方法：通过查阅相关文献，
关注，并访问PubMed，ISI和其他网站。
结果：绝大多数人畜共患病是在动物宿主中维持的，应引起重视。这些疾病，
如钩端螺旋体病、Q热、布鲁氏菌病等，其中布鲁氏菌病可通过
密切接触受感染的动物或食用未经高温消毒的奶制品。因此，根除这种
人类群体中感染取决于动物中可能方法中的遗漏
水库这些方法就像牲畜的试验屠宰和疫苗接种。因此，接种疫苗不是
这是唯一的控制方法，但它可能是经济的。
结论：目前尚无有效的疫苗可用于人类控制该病。的
课程介绍了一些不同的疫苗，这种感染的牲畜，裂解活减毒，杀死
细菌和亚单位。因此，对于根除这种疾病，一些疫苗更有效
保护和较少的副作用是必要的。
Objective: Brucellosis is considered as an important zoonotic and worldwide infection with more than
half of million human cases, which it occurs more and more in animals like as wild and live stocks. Sheep,
cattle, and goats are animal samples that listed. Symptoms of this disease in human are consisted of:
undulant fever, back pains, faint, spondylitis, arthritis and orchitis. This infection causes abortion in
livestock, and this point is one of the important economic losses. Reduction in milk production is another
problem in this disease too.
Materials and Methods: This study is conducted by reviewing of the literatures, which are related to this
concern, and also visiting PubMed, ISI and other websites.
Results: We must pay heed that most zoonoses are maintained in the animal reservoir. These diseases,
such as leptospirosis, Q-fever, brucellosis etc. which among them brucellosis can transfer to human via
close contact with infected animals or consumption of unpasteurized dairy. Therefore, eradication of this
infection in human population is depended on omission of that in possible methods among animals
reservoir. Such methods are like test-slaughter and vaccination of livestock. Hence, vaccination is not
alone method for controlling, but it is probably economic one.
Conclusion: Nowadays a vaccine which is effective for this disease control in human is not available. Of
course presented some different vaccines for this infection in livestock that cleave live attenuated, killed
bacteria and sub unit. Therefore, for eradication of this disease some vaccines with more effectiveness
protection mid fewer side effects are necessary.