PERSPECTIVES ON PRECISION HEALTH AMONG RACIAL/ETHNIC MINORITY COMMUNITIES AND THE PHYSICIANS THAT SERVE THEM
PERSPECTIVES ON PRECISION HEALTH AMONG RACIAL/ETHNIC MINORITY COMMUNITIES AND THE PHYSICIANS THAT SERVE THEM
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DOI：
10.18865/ed.30.s1.137
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发表时间：
2020-04-01
影响因子：
3.2
通讯作者：
Martin, Christopher
中科院分区：
文献类型：
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作者：
Rosas, Lisa G.;Nasrallah, Catherine;Martin, Christopher
背景：为了精确医疗解决健康差异，不同种族/少数民族社区和为他们服务的医生的参与至关重要。方法：采用以社区为基础的参与式研究方法，采用混合方法，深入了解美洲印第安人、非洲裔美国人、拉丁裔、华人和越南群体以及为这些社区服务的医生的精准健康研究和实践。一项调查评估了人口统计数据和对精准健康、基因检测和精准健康研究的看法。每个种族/少数民族群体和医生的焦点小组（n=12）进一步探讨了对这些话题的态度。结果：100名社区成员（美洲印第安人[n=17]、非洲裔美国人[n=13]、华裔[n=17]、拉丁裔[n=27]、越南裔[n=26]）和14名医生完成调查并参与焦点小组。社区成员对精准健康的熟悉程度较低，而医生对精准健康的熟悉程度较高。大多数群体都对这种方法充满热情，特别是如果它考虑到除基因外对健康的影响（例如，环境、行为、社会因素）。非裔美国人和美国印第安人与会者对基于过去生物医学研究中滥用行为的精确保健做法和研究表示严重关切。此外，医生和社区成员还共同关注遗传信息的安全性和保密性、基因检测和精准医疗的成本和可负担性、歧视和差异、对医疗和研究及制药机构的不信任、语言障碍以及医生的专业等问题。结论：少数族裔社区和为他们服务的提供者的参与对于推进精确健康方法解决健康差异非常重要。
Background: In order for precision health to address health disparities, engagement of diverse racial/ethnic minority communities and the physicians that serve them is critical.Methods: A community-based participatory research approach with mixed methods was employed to gain a deeper understanding of precision health research and practice among American Indian, African American, Latino, Chinese, and Vietnamese groups and physicians that serve these communities. A survey assessed demographics and opinions of precision health, genetic testing, and precision health research. Focus groups (n=12) with each racial/ethnic minority group and physicians further explored attitudes about these topics.Results: One hundred community members (American Indian [n=17], African American [n=13], Chinese [n=17], Latino [n=27], and Vietnamese [n=26]) and 14 physicians completed the survey and participated in the focus groups. Familiarity with precision health was low among community members and high among physicians. Most groups were enthusiastic about the approach, especially if it considered influences on health in addition to genes (eg, environmental, behavioral, social factors). Significant concerns were expressed by African American and American Indian participants about precision health practice and research based on past abuses in biomedical research. In addition, physician and community members shared concerns such as security and confidentiality of genetic information, cost and affordability of genetic tests and precision medicine, discrimination and disparities, distrust of medical and research and pharmaceutical institutions, language barriers, and physician's specialty.Conclusions: Engagement of racial/ethnic minority communities and the providers who serve them is important for advancing a precision health approach to addressing health disparities.