Serum albumin level and nosocomial pneumonia in stroke patients
Serum albumin level and nosocomial pneumonia in stroke patients
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DOI：
10.1111/j.1468-1331.2006.01210.x
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发表时间：
2006-03-01
影响因子：
5.1
通讯作者：
Szczudlik, A
中科院分区：
文献类型：
--
作者：
Dziedzic, T;Pera, J;Szczudlik, A
低白蛋白血症与感染风险增加有关。本研究的目的是确定血清白蛋白水平是否是卒中患者医院获得性肺炎的独立预测因子。回顾性分析705例脑卒中发病后24 h内入院的连续缺血性脑卒中患者的资料。在卒中发作后36 h内测定血清白蛋白水平。10.5%的脑卒中患者发生医院获得性肺炎。肺炎患者的血清白蛋白水平显著低于非肺炎患者（31.9 +/- 7.5 g/l vs. 35.5 +/- 6.9 g/l），多变量分析显示血清白蛋白水平与肺炎风险相关（OR：0.95，95% CI：0.91-0.98）。我们的研究结果表明，血清白蛋白水平是脑卒中患者医院获得性肺炎的独立预测因子。
Hypoalbuminemia is associated with increased risk of infections. The aim of this study was to determine if serum albumin level is an independent predictor of nosocomial pneumonia in stroke patients. Data of 705 consecutive ischemic stroke patients admitted within 24 h after stroke onset were analyzed retrospectively. Serum albumin level was measured within 36 h after stroke onset. Nosocomial pneumonia was found in 10.5% of stroke patients. Patients with pneumonia had significantly lower serum albumin level than those without pneumonia (31.9 +/- 7.5 g/l vs. 35.5 +/- 6.9 g/l) and serum albumin level was associated with risk of pneumonia on multivariate analysis (OR: 0.95, 95% CI: 0.91-0.98). Our results show that serum albumin level is an independent predictor of nosocomial pneumonia in stroke patients.