Photoperiod and temperature can regulate body mass, serum leptin concentration, and uncoupling protein 1 in Brandt's voles (Lasiopodomys brandtii) and Mongolian gerbils (Meriones unguiculatus)
Photoperiod and temperature can regulate body mass, serum leptin concentration, and uncoupling protein 1 in Brandt's voles (Lasiopodomys brandtii) and Mongolian gerbils (Meriones unguiculatus)
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光周期和温度可以调节布氏田鼠 (Lasiopodomysbrandtii) 和蒙古沙鼠 (Meriones unguiculatus) 的体重、血清瘦素浓度和解偶联蛋白 1
DOI：
10.1086/513189
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发表时间：
2007-05-01
影响因子：
1.6
通讯作者：
Wang, De-Hua
中科院分区：
文献类型：
--
作者：
Li, Xing-Sheng;Wang, De-Hua
环境因素在野生小型哺乳动物的体质量季节性适应和产热过程中起着重要作用。在这项研究中，我们进行了析因实验(温度x光周期)，在此实验中，布氏田鼠和光周期蒙古沙土鼠适应不同的光周期(长光周期，16L：8D；短光周期，8L：16D)和温度(暖，23摄氏度；冷，5摄氏度)，以验证光周期、温度或两者共同作用可以触发血清瘦素水平、体质量、产热和能量摄入的季节性变化的假设。我们的数据表明，在寒冷和短光周期中，勃兰特田鼠的体重都出现了显著的下降。然而，暴露在类似条件下的沙土鼠的体重没有发现明显的变化。短光周期导致田鼠和沙土鼠血清瘦素水平下降，这可能是导致能量摄入增加的原因之一。此外，短光周期诱导了田鼠和沙土鼠体内解偶联蛋白1(UCP1)含量的增加，寒冷进一步促进了田鼠体内解偶联蛋白1的增加。这两个物种的光周期和温度之间没有交互作用。勃兰特田鼠可以通过改变能量摄入和消耗来减少体重，而蒙古沙鼠则可以在冬季条件下通过平衡能量代谢来保持体重相对稳定。瘦素可能参与了这两个物种的体重和生热能力的调节。
Environmental factors play an important role in the seasonal adaptation of body mass and thermogenesis in wild small mammals. In this study, we performed a factorial experiment (temperature x photoperiod) in which Brandt's voles and temperature photoperiod Mongolian gerbils were acclimated to different photoperiods (long photoperiod, 16L : 8D; short photoperiod, 8L : 16D) and temperatures (warm, 23 degrees C; cold, 5 degrees C) to test the hypothesis that photoperiod, temperature, or both together can trigger seasonal changes in serum leptin level, body mass, thermogenesis, and energy intake. Our data demonstrate that Brandt's voles showed a remarkable decrease in body mass in both the cold and a short photoperiod. However, no significant changes in body mass were found for gerbils exposed to similar conditions. The short photoperiod induced a decrease in serum leptin levels for both voles and gerbils that might contribute to an increase in energy intake. Furthermore, the short photoperiod induced an increase of uncoupling protein 1 (UCP1) content for both voles and gerbils, and cold can further enhance the increase in voles. No interactions between photoperiod and temperature were detected for the two species. Brandt's voles can decrease their body mass through changes in energy intake and expenditure, while Mongolian gerbils can keep body mass relatively stable by balancing energy metabolism under winterlike conditions. Leptin was potentially involved in the regulation of body mass and thermogenic capacity for the two species.