Regio- and Stereoselective Addition of Ketene Silyl Acetals to Quinolinium Salts by Way of an Intramolecular C=O···Qu+ or C=S···Qu+ Interaction
Regio- and Stereoselective Addition of Ketene Silyl Acetals to Quinolinium Salts by Way of an Intramolecular C=O···Qu+ or C=S···Qu+ Interaction
复制标题
通过分子内 C=O·Qu+ 或 C=S·Qu+ 相互作用将烯酮甲硅烷基缩醛与喹啉盐进行区域和立体选择性加成
DOI：
10.1246/cl.2001.1034
复制
发表时间：
2001
影响因子：
1.6
通讯作者：
C. Morita
中科院分区：
文献类型：
--
作者：
S. Yamada;C. Morita
手性 1,4-二氢喹啉是通过将乙烯酮甲硅烷基缩醛加成到喹啉鎓盐来合成的。 1H NMR 光谱和 X 射线分析揭示了立体选择性与喹啉鎓和羰基或硫代羰基之间的分子内相互作用有关。
Chiral 1,4-dihydroquinolines were synthesized by the addition of ketene silyl acetals to quinolinium salts. The stereoselectivity was associated with the intramolecular interaction between the quinolinium and the carbonyl or thiocarbonyl groups, which was revealed by 1H NMR spectroscopy and X-ray analysis.