TNM residual tumor classification revisited
TNM residual tumor classification revisited
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DOI：
10.1002/cncr.10492.abs
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发表时间：
2002-05-01
期刊：
影响因子：
6.2
通讯作者：
Sobin, LH
中科院分区：
文献类型：
--
作者：
Wittekind, C;Compton, CC;Sobin, LH
背景。对于癌症患者来说，在癌症定向手术时肿瘤切除的完整性或非手术治疗后疾病缓解对预后有很大影响。这些参数定义了最终治疗的相对成功，并可以通过TNM系统中的另一个亚分类，残余肿瘤(R)分类来编码。尽管残余肿瘤状态在治疗后的临床管理设计中具有重要意义，但R分类经常出现误解和不一致的应用，从而减少或废除了其临床应用。对相关文献进行了R分级的使用和预后重要性分析。本研究讨论了R分级对不同类型肿瘤预后的重要性。描述了使用R分类时出现的问题。关于使用模具R分类的特殊问题得到解决。如果采用一致的方式，R分类是预后的有力指标，有助于比较治疗结果。统一使用和解释这一分类对于处理后数据收集的标准化至关重要。(C) 2002年美国癌症协会。
BACKGROUND. For cancer patients, prognosis is strongly influenced by the completeness of tumor removal at the time of cancer-directed surgery or disease remission after nonsurgical treatment with curative intent. These parameters define the relative success of definitive treatment and can be codified by an additional subclassification within the TNM system, the residual tumor (R) classification. Despite the importance of residual tumor status in designing clinical management after treatment, misinterpretation and inconsistent application of the R classification frequently occur that diminish or abrogate its clinical utility.METHODS. An analysis of the relevant literature regarding the use and prognostic importance of the R classification was undertaken.RESULTS. In the current study, the prognostic importance of the R classification for different kinds of tumors is discussed. Problems that arise in using the R classification are described. Special issues regarding the use of die R classification are addressed.CONCLUSIONS. The R classification is a strong indicator of prognosis and facilitates the comparison of treatment results if applied in a consistent manner. Uniform use and interpretation of this classification is essential for the standardization of posttreatment data collection. (C) 2002 American Cancer Society.