Hypertonic saline for hyponatremia: Risk of inadvertent overcorrection
Hypertonic saline for hyponatremia: Risk of inadvertent overcorrection
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DOI：
10.2215/cjn.00910207
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发表时间：
2007-11-01
影响因子：
9.8
通讯作者：
Sterns, Richard H.
中科院分区：
文献类型：
--
作者：
Mohmand, Hashim K.;Issa, Dany;Sterns, Richard H.
背景和目的：关于使用高渗盐水治疗低钠血症的剂量-反应关系的数据非常有限。本研究的目的是评估先前发布的指南的遵守情况(将校正率限制在每48小时18 mEq/L。没有患者的校正率达到每48小时25 mEq/L。在血清钠患者中
Background and objectives: Data regarding dosage-response relationships for using hypertonic saline in treatment of hyponatremia are extremely limited. Objectives of this study were to assess adherence to previously published guidelines (limiting correction to 18 mEq/L per 48 h. No patient's rate was corrected by >25 mEq/L per 48 h. Among patients with serum sodium