The synthesis of 4,4′-arylmethylene-bis(3-(trifluoromethyl)-1-phenyl-1H-pyrazol-5-ol) in aqueous media without catalyst
The synthesis of 4,4′-arylmethylene-bis(3-(trifluoromethyl)-1-phenyl-1H-pyrazol-5-ol) in aqueous media without catalyst
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DOI：
10.1016/j.jfluchem.2006.10.006
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发表时间：
2007-02
影响因子：
1.9
通讯作者：
Changsheng Yao;Chenxia Yu;S. Tu;D. Shi;Xiang-Shan Wang;You-Quan Zhu;Hua-zheng Yang
中科院分区：
文献类型：
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作者：
Changsheng Yao;Chenxia Yu;S. Tu;D. Shi;Xiang-Shan Wang;You-Quan Zhu;Hua-zheng Yang
在无催化剂的水相中，以1-苯基-3-三氟甲基吡唑-5-酮和芳香醛为原料，合成了4，4 ′-芳亚甲基-双（3-三氟甲基-1-苯基-1H-吡唑-5-醇）。所得化合物均经元素分析、红外光谱和核磁共振氢谱表征。化合物3g的结构经X-射线单晶衍射进一步证实。该方法具有反应条件温和、无催化剂、产率高、环境友好等优点。
The synthesis of 4,4′-arylmethylene-bis(3-(trifluoromethyl)-1-phenyl-1H-pyrazol-5-ol) was performed effectively in aqueous media without catalyst by the reaction of aryl aldehydes and 1-phenyl-3-trifluoromethylpyrazol-5-one. All of the compounds obtained were characterized by elemental analysis, FTIR and1H NMR. The structure of compound 3g was further confirmed by the X-ray single crystal diffraction. The method has the advantages of mild condition, without any catalyst, high yields and environmentally benign procedure.