Evaluation of kidney injury molecule-1 as a disease progression biomarker in diabetic nephropathy
Evaluation of kidney injury molecule-1 as a disease progression biomarker in diabetic nephropathy
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DOI：
10.12669/pjms.35.4.154
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发表时间：
2019-07-01
影响因子：
2.2
通讯作者：
Shahid, Sana
中科院分区：
文献类型：
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作者：
Khan, Fatima Abid;Fatima, Syeda Sadia;Shahid, Sana
背景与目的：肾损伤分子-1(KIM-1)是一种肾小管损伤特异释放到循环中的多肽。本研究旨在评估有和无肾脏疾病的糖尿病患者肾脏损伤分子-1的水平。并评价Kim-1作为进展性肾损害早期筛查标记物的作用。方法：这项随访研究包括2016年11月至2017年9月来自真纳研究生医学中心(JPMC)糖尿病门诊的85名患者，他们被分为：i)A1组(n=30)糖尿病患者
Background & Objective: Kidney Injury Molecule-1 (KIM-1) is a peptide whose release into circulation is specific to tubular injury. This study aimed to estimate levels of kidney injury molecule-1 in diabetic patients with and without kidney disease. And evaluate the role of KIM-1 as an early screening marker of progressive kidney injury.Methods: This follow-up study included n=85 subjects from the diabetic clinic of Jinnah Post Graduate Medical Center (JPMC) in collaboration with Aga Khan University from November 2016 till September 2017 They were divided as: i) Group A1 (n=30) participants with diabetes for