Predictors of persistence and remission of ADHD into adolescence: Results from a four-year prospective follow-up study
Predictors of persistence and remission of ADHD into adolescence: Results from a four-year prospective follow-up study
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DOI：
10.1097/00004583-199603000-00016
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发表时间：
1996-03-01
影响因子：
13.3
通讯作者：
Spencer, T
中科院分区：
文献类型：
--
作者：
Biederman, J;Faraone, S;Spencer, T
目的：探讨注意缺陷多动障碍（ADHD）持续时间和缓解时间的预测因素。方法：研究对象为6- 17岁的白人，非西班牙裔男孩，有或没有多动症。在4年的随访评估中，采用DSM-III-R结构化诊断访谈和盲评量表来检查精神病学诊断、认知成就、社会、学校和家庭功能。结果：在4年的随访评估中，85%的ADHD儿童继续存在这种障碍，15%的儿童得到缓解。在戒烟者中，一半是在童年，另一半是在青春期。持续性的预测因子是ADHD的熟悉程度、社会心理逆境、行为、情绪和焦虑障碍的共病。结论：研究结果前瞻性地证实，大多数ADHD儿童在4年后仍会表现出这种障碍。对于少数儿童来说，多动症是一种短暂的疾病，在发育早期就会缓解。此外，我们已经证明ADHD的持续存在是可以预测的。熟悉、逆境和精神共病可能是临床上有用的ADHD儿童持续性障碍风险的预测因子。
Objective: To evaluate the predictors of persistence and the timing of remission of attention-deficit hyperactivity disorder (ADHD). Method: Subjects were 6- to 17-year old Caucasian, non-Hispanic boys with and without ADHD. DSM-III-R structured diagnostic interviews and blind raters were used to examine psychiatric diagnoses, cognitive achievement, social, school, and family functioning at a 4-year follow-up assessment. Results: At the 4-year follow-up assessment, 85% of children with ADHD continued to have the disorder and 15% remitted. Of those who remitted, half did so in childhood and the other half in adolescence. Predictors of persistence were familiality of ADHD, psychosocial adversity, and comorbidity with conduct, mood, and anxiety disorders. Conclusions: The findings prospectively confirm that the majority of children with ADHD will continue to express the disorder 4 years later. For a minority of children, ADHD was a transient disorder that remits early in development. In addition, we have shown that persistence of ADHD is predictable. Familiality, adversity, and psychiatric comorbidity may be clinically useful predictors of which children with ADHD are at risk for a persistent disorder.