Sterilization of medical equipment using radicals produced by oxygen/water vapor RF plasma

Sterilization of medical equipment using radicals produced by oxygen/water vapor RF plasma
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DOI:
10.1143/jjap.45.8358
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发表时间:
2006-10-01
期刊:
JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS BRIEF COMMUNICATIONS & REVIEW PAPERS
影响因子:
--
通讯作者:
Hanada, Yasushi
Hanada, Yasushi
中科院分区:
其他
文献类型:
--
作者:
Hayashi, Nobuya;Guan, Weimin;Hanada, Yasushi

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使用低压RF放电等离子体对医疗设备进行灭菌。氧自由基作为灭菌的氧化材料,由氧气或水蒸气产生。使用等离子体的光发射光谱确认了原子氧和OH自由基的产生。在失活过程中,放电区的压力周期性地变化,以有效地产生自由基并将所产生的自由基渗透到微小的间隙中。微生物检测培养基片表明,使用n(e)= 10(9)cm(-3)的氧等离子体和水蒸气等离子体,活性芽孢杆菌的十进制减少值分别为5和8 min。生物指示剂表明,在90分钟的处理时间内,芽孢杆菌孢子的灭菌是成功的。
The sterilization of medical equipment was performed using low-pressure RF discharge plasma. Oxygen radicals as oxidizing materials for sterilization were produced from oxygen or water vapor. The generation of atomic oxygen and OH radicals was confirmed using the light emission spectra of the plasma. The pressure in the discharge region was varied periodically during inactivation in order to produce radicals effectively and to penetrate the produced radicals into tiny gaps. Medium sheets for microbial detection indicated that the decimal reduction value of active bacillus was 5 and 8 min using oxygen plasma and water vapor plasma with n(e) = 10(9) cm(-3), respectively. Biological indicators clarified that the sterilization of bacilli spores was successful for a treatment time of 90 min.