???????Visual Function in Children With Posterior Lens Opacities Before and After Surgery
???????Visual Function in Children With Posterior Lens Opacities Before and After Surgery
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???????儿童后透镜混浊手术前后视功能的变化
DOI：
10.1016/j.ajo.2022.04.018
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发表时间：
2022-09-01
影响因子：
4.2
通讯作者：
Chen, W. E. I. R. O. N. G.
中科院分区：
文献类型：
--
作者：
Chen, W. A. N.;Chen, H. U., I;Chen, W. E. I. R. O. N. G.
目的：探讨先天性后晶状体混浊患儿白内障手术前后的视功能及影响视力的相关因素。设计：前瞻性病例系列研究。方法：本研究招募了接受白内障手术的儿童后晶状体混浊患者。围手术期检查白内障类型、位置、混浊面积及斜视。测定白内障手术前后的视灵敏度、调节传递函数（MTF）、眼像差和立体视。结果：63例患者69只眼。手术患者的平均年龄为6.5±2.9岁。视功能包括矫正距离视力（CDVA）、MTF截止频率和眼像差在后晶状体混浊的眼睛中受到显著影响。术后CDVA由最小分辨角（logMAR）的0.81 +/- 0.53对数显著改善至0.40 +/- 0.40对数（P < 0.001）。39例（56.5%）患者最终VA达到20/40或更好。术后MTF截止值明显提高，总眼像差明显降低（P < 0.001）。术后立体视功能明显改善（P < 0.001）。术后CDVA危险因素的多因素分析显示术前CDVA恶化、晶状体混浊较大、平均角膜度数为危险因素（均P < 0.05）。结论：儿童后晶状体混浊视力明显下降，手术治疗可有效改善视力。CDVA≥0.52 logMAR、晶状体混浊度< 6.5 mm(2)、平均角膜度数较小的患者术后CDVA较大。(C) 2022, Elsevier Inc.出版
PURPOSE: To evaluate the visual function before and after cataract surgery in children with congenital posterior lens opacities as well as the factors associated with a good visual outcome. DESIGN: Perspective case-series study. METHODS: Pediatric patients with posterior lens opacities who underwent cataract surgery were recruited in this study. The cataract type, location, area of opacities, and strabismus were examined perioperatively. Moreover, visual acuity, modulation transfer function (MTF), ocular aberrations, and stereopsis were measured before and after cataract surgery. RESULTS: Sixty-nine eyes of 63 patients were studied. The mean age of patients at surgery was 6.5 +/- 2.9 years. Visual function including corrected distance visual acuity (CDVA), MTF cutoff frequency, and ocular aberrations were significantly affected in eyes with posterior lens opacities. Postoperatively, CDVA was significantly improved from 0.81 +/- 0.53 logMAR to 0.40 +/- 0.40 logarithm of the minimum angle of resolution (logMAR) (P < .001). Thirty-nine patients (56.5%) achieved a final VA of 20/40 or better. Moreover, MTF cutoff values were significantly improved, and total ocular aberrations were decreased after cataract removal (both P < .001). The stereopsis was also improved postoperatively (P < .001). The multivariate analysis of the risk factors for postoperative CDVA showed that worse preoperative CDVA, larger size of lens opacities, and mean keratometry were the risk factors (all P < .05). CONCLUSIONS: Visual function can be significantly decreased in children with posterior lens opacities, and surgery was effective in improving visual function. Patients with a CDVA of 0.52 logMAR or better, a size of lens opacity < 6.5 mm(2) and smaller mean keratometry had a greater CDVA postoperatively. (C) 2022Published by Elsevier Inc.