The incorporation of large impurities into virus crystals.
The incorporation of large impurities into virus crystals.
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将大量杂质掺入病毒晶体中。
DOI：
10.1107/s0907444904030756
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
McPherson,Alexander
中科院分区：
文献类型：
--
作者：
Kuznetsov,YuG;Makino,DeboraL;Malkin,AlexanderJ;McPherson,Alexander
病毒晶体可以包含大量不寻常的杂质，这是常规晶体所不可能的，甚至是大多数蛋白质晶体，因为它们的组成颗粒尺寸很大。这些杂质包括异常病毒体、卫星病毒和生物纤维。这里列举了几种不寻常杂质的例子，沿着了它们对晶格的影响。高溶剂含量、晶格的宽容特性和病毒粒子的可塑性使这些纯化成为可能。
Virus crystals can incorporate a wide range of unusual impurities, not possible for conventional crystals, or even most protein crystals because of the large size of their constituent particles. These impurities include anomalous virions, satellite viruses and biological fibers. Examples of several of these unusual impurities are presented here, along with some of the consequences for the crystal lattices. The high solvent content, the forgiving character of the lattice and the plasticity of the virions allow these incorporations to be possible.