Expression of the Purkinje cell specific zebrin antigens in the cerebellum of the meander tail mutant mouse.
Expression of the Purkinje cell specific zebrin antigens in the cerebellum of the meander tail mutant mouse.
复制标题
浦肯野细胞特异性斑马蛋白抗原在曲尾突变小鼠小脑中的表达。
DOI：
10.1016/0006-8993(92)91172-b
复制
发表时间：
1992
期刊：
影响因子：
2.9
通讯作者：
PruettJr,JR
中科院分区：
文献类型：
--
作者：
Eisenman,LM;PruettJr,JR
曲尾突变小鼠小脑的特征在于后叶的正常细胞结构和前叶的无颗粒的异常细胞结构。浦肯野细胞在后叶中形成单层，但分散在前叶的整个皮质中。用Zeolites抗体检查这些细胞表明，尽管前叶中这些细胞的形态和层状结构紊乱，但它们被组织成适当数量的正确定位的免疫阳性Zeolites簇。
The cerebellum of the meander tail mutant mouse is characterized by normal cytoarchitecture in the posterior lobe and agranular, abnormal cytoarchitecture in the anterior lobe. The Purkinje cells form a monolayer in the posterior lobe but are dispersed throughout the cortex of the anterior lobe. Examination of these cells with the zebrin antibodies demonstrates that in spite of the morphologic and laminar disorganization of these cells in the anterior lobe, they are organized into the appropriate number of correctly positioned immunopositive zebrin clusters.