Temperature effects on isometric contractions of slow and fast twitch muscles of various rodents--dependence on fibre type composition: a comparative study.
Temperature effects on isometric contractions of slow and fast twitch muscles of various rodents--dependence on fibre type composition: a comparative study.
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温度对各种啮齿动物慢肌和快肌等长收缩的影响——纤维类型组成的依赖性：一项比较研究。
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
U. Gaunitz
中科院分区：
文献类型：
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作者：
G. Asmussen;U. Gaunitz
本文研究了温度（15-37 ℃）对小鼠、大鼠和豚鼠慢肌比目鱼肌（SOL）和快肌趾长伸肌（EDL）等长收缩的影响。冷却的浴溶液延长的时间参数的单抽搐和强直性收缩在所有动物的两种肌肉类型中以非线性的方式。在所有动物的主要含有快速收缩纤维（如EDL）的肌肉中，冷却后单收缩张力增加（冷增强），在约20 ℃时最大值为160-180%。温度降低对三种动物SOL的抽搐张力的影响是不同的。在小鼠的SOL（含有约50%的慢颤肌纤维）中，观察到颤肌张力几乎不变，在大鼠的SOL（约70%的慢颤肌纤维）中观察到中度冷抑制，在豚鼠的SOL（仅由慢颤肌纤维组成）中观察到强烈的冷抑制。最大强直张力逐渐下降冷却在所有的肌肉和独立的纤维类型组成。冷却增加了快速收缩肌肉的收缩-强直-比率，而降低了纯慢收缩肌肉的收缩-强直-比率。它的结论是温度依赖性的单颤和颤-强直比可以被用作一个给定的肌肉的纤维类型组成的生理措施。
The influence of temperature (range 15-37 degrees C) on the isometric contractions of the slow twitch soleus (SOL) and the fast twitch extensor digitorum longus (EDL) muscles of mice, rats and guinea pigs were investigated in vitro. Cooling of the bathing solution prolonged the time parameters of single twitches and tetanic contractions in a non-linear manner in both muscle types of all animals. In muscles containing predominately fast twitch fibres like the EDL of all animals cooling was followed by an increase of the single twitch tension (cold potentiation) with a maximum of 160-180% at about 20 degrees C. The influence of a decrease of the temperature on the twitch tension was different in the SOL of the three animals. In SOL of mice (containing about 50% slow twitch fibres) the twitch tension was virtually unchanged, in SOL of rats (about 70% slow twitch fibres) a moderate cold depression and in SOL of guinea pigs (composed by slow twitch fibres only) a strong cold depression was observed. The maximum tetanic tension decreased progressively on cooling in all muscles and independently of their fibre type composition. Cooling increased the twitch-tetanus-ratio in fast twitch and decreased it in pure slow twitch muscles. It is concluded that the temperature dependence of the single twitch and the twitch-tetanus-ratio can be used as a physiological measure of the fibre type composition of a given muscle.