Quality of Life Assessment for Acute Heart Failure Patients From Emergency Department Presentation Through 30 Days After Discharge: A Pilot Study With the Kansas City Cardiomyopathy Questionnaire
Quality of Life Assessment for Acute Heart Failure Patients From Emergency Department Presentation Through 30 Days After Discharge: A Pilot Study With the Kansas City Cardiomyopathy Questionnaire
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DOI：
10.1016/j.cardfail.2013.11.010
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发表时间：
2014-01-01
影响因子：
6
通讯作者：
Pang, Peter S.
中科院分区：
文献类型：
--
作者：
Sauser, Kori;Spertus, John A.;Pang, Peter S.
背景：对于急性心力衰竭（HF），目前还没有经过良好验证的患者报告的疾病状态仪器。我们评估了在急性心力衰竭住院期间使用堪萨斯城心肌病问卷（KCCQ）的可行性，以及急性变化与30天再入院的关系。方法和结果：选取方便的急性心衰患者样本，在入院、出院和出院后30天给予KCCQ。我们检查了KCCQ评分随时间的平均差异，并通过再入院状态进行分层，使用t检验和逻辑回归来检查基于医院的变化差异。52例患者（平均年龄63±35岁，56.9%为男性，46.2%为白人），出院和30天评估的完成率均为90%。入院时评分最低，住院期间评分提高，30天评分最高。就诊至出院的平均变化为+11.9 +/- 97.0 (P = 0.007)，出院至30天的平均变化为+19.8 +/- 87.8 （P < 0.001）。随访30天，10例患者再次入院，再入院患者与未再入院患者住院期间评分变化无显著差异（再入院患者：+4.8 +/- 81.5 vs +16.2 +/- 27.4; P = 0.32）。结论：在这项初步研究中，KCCQ在急性心衰住院期间是可行的，并且对急性变化具有敏感性，但住院期间的评分变化并不能预测30天的再入院。
Background: There are no well validated patient-reported disease status instruments for acute heart failure (HF). We assessed the feasibility of using the Kansas City Cardiomyopathy Questionnaire (KCCQ) during acute heart failure hospitalization, and the association of acute changes with 30-day readmission.Methods and Results: A convenience sample of acute HF patients were administered the KCCQ on presentation, discharge, and 30 days after discharge. We examined mean differences in KCCQ scores over time, and we stratified by readmission status to examine differences in hospital-based changes with the use of t test and logistic regression. Among 52 patients (mean age 63 +/- 35 years, 56.9% male, 46.2% white), discharge and 30-day assessments were each completed by 90%. Scores were lowest at presentation, improved during hospitalization, and were highest at 30 days. The mean change was +11.9 +/- 97.0 (P = .007) between presentation and discharge and +19.8 +/- 87.8 (P < .001) between discharge and 30 days. Within the 30-day follow-up, 10 patients were readmitted, and there were no significant differences in score changes during hospitalization between patients with and without readmission (readmitted patients: +4.8 +/- 81.5 vs no readmission +16.2 +/- 27.4; P = .32).Conclusions: In this pilot study, the KCCQ is feasible to use during acute HF hospitalizations and demonstrates sensitivity to acute changes, but score changes during hospitalization did not predict 30-day readmission.