Predictors of meaningful improvement in quality of life after temporal lobe epilepsy surgery: A prospective study
Predictors of meaningful improvement in quality of life after temporal lobe epilepsy surgery: A prospective study
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DOI：
10.1111/epi.13721
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发表时间：
2017-05-01
期刊：
影响因子：
5.6
通讯作者：
Walz, Roger
中科院分区：
文献类型：
--
作者：
Pauli, Carla;Schwarzbold, Marcelo Liborio;Walz, Roger
目的：前瞻性研究巴西患者前颞叶切除术（ATL）治疗与海马硬化相关的耐药内侧颞叶癫痫（MTLE-HS）后生活质量（QOL）最小临床重要变化（MCIC）的独立预测因素。进行多元二元逻辑回归分析以确定临床、人口统计学、放射学，癫痫生活质量-31量表中与MCIC独立相关的电生理变量77例单侧MTLE-HS患者在ATL后1年的QOLIE-31总分。总体QOLIE-31评分及其所有子量表评分均显著增加（p
Objectives: To investigate prospectively the independent predictors of a minimum clinically important change (MCIC) in quality of life (QOL) after anterior temporal lobectomy (ATL) for drug-resistant mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS) in Brazilian patients.Methods: Multiple binary logistic regression analysis was performed to identify the clinical, demographic, radiologic, and electrophysiologic variables independently associated with MCIC in the Quality of Life in Epilepsy-31 Inventory (QOLIE-31) overall score 1year after ATL in 77 consecutive patients with unilateral MTLE-HS.Results: The overall QOLIE-31 score and all its subscale scores increased significantly (p