Enhancing the Angular Sensitivity of Plasmonic Sensors Using Hyperbolic Metamaterials.
Enhancing the Angular Sensitivity of Plasmonic Sensors Using Hyperbolic Metamaterials.
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DOI：
10.1002/adom.201600448
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发表时间：
2016-11
影响因子：
9
通讯作者：
Strangi G
中科院分区：
文献类型：
--
作者：
Sreekanth KV;Alapan Y;ElKabbash M;Wen AM;Ilker E;Hinczewski M;Gurkan UA;Steinmetz NF;Strangi G
表面等离子体共振（SPR）传感器主要基于棱镜和光栅耦合技术，光谱扫描和角度扫描是两种主要的询问方案。其中，角扫描技术具有信噪比高、测量精度高等优点。目前可用的SPR传感器布置提供每个RIU 500°-600°的最大角度灵敏度。在这里，我们报告的研究光栅耦合双曲型超材料（GC-HMM）传感器具有高的角度灵敏度。实验研究表明，通过激发与双曲型超材料相关的体等离子体激元，从可见光到近红外（NIR）波长的角度灵敏度非常高，每个RIU的最大角度为7000°。这种角扫描等离子体生物传感器已被用于检测低分子量的生物分子，如生物素（244 Da）和高分子量的大分子，如豇豆花叶病毒（CPMV，5.6 × 106 Da）在超低浓度。微型化的传感装置可以与微流体系统集成，用于开发下一代生物传感器，用于芯片实验室和即时护理应用。
Surface plasmon resonance (SPR) sensors operate mainly on prism and grating coupling techniques, with spectral and angular scans being the two major interrogation schemes. Among them, the angular scan technique has several advantages including higher measurement precision owing to its higher signal-to-noise ratio. The currently available SPR sensor arrangements provide a maximum angular sensitivity of 500°–600° per RIU. Here, we report the study of grating coupled-hyperbolic metamaterial (GC-HMM) sensors with high angular sensitivity. The experimental studies show extraordinary angular sensitivities from visible to near infrared (NIR) wavelengths by exciting bulk plasmon polaritons associated with hyperbolic metamaterials, with a maximum of 7000° per RIU. This angular-scan plasmonic biosensor has been used for the detection of low molecular weight biomolecules such as biotin (244 Da) and high molecular weight macromolecules such as Cowpea mosaic virus (CPMV, 5.6 × 106 Da) at ultralow concentrations. The miniaturized sensing device can be integrated with microfluidic systems for the development of next-generation biosensors for lab-on-a-chip and point-of-care applications.