Information technology and the role of WMDA in promoting standards for international exchange of hematopoietic stem cell donors and products
Information technology and the role of WMDA in promoting standards for international exchange of hematopoietic stem cell donors and products
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DOI：
10.1038/bmt.2010.29
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发表时间：
2010-05-01
影响因子：
4.8
通讯作者：
Rist, H-G
中科院分区：
文献类型：
--
作者：
Maiers, M.;Bakker, J. N. A.;Rist, H-G
在全球范围内促成的无关的造血干细胞移植中，近一半涉及国家之间的产品交换。这一过程是信息密集型的，需要通过人口、临床和遗传信息、实验室样本和结果等复杂数据交易的区域枢纽进行协调。每个登记处都开发了自己独特的系统来表示导致移植的数据和过程。WMDA信息技术工作组成立于2001年秋季，作为一个论坛，讨论和制定支持造血干细胞登记的信息技术标准。它的成员包括来自WMDA成员注册处的IT专家。该小组的标准化工作集中在三个领域：人类白细胞抗原和其他数据领域的验证和似是而非控制的标准化参考数据集；确定组织兼容性的匹配算法标准；登记册之间的通信标准。骨髓移植(2010年)45839-842；DOI：10.1038/bmt.2010.29；2010年3月1日在线发布
Nearly half of the unrelated hematopoietic SCTs facilitated worldwide involves an exchange of products between countries. The process is information intensive and requires coordination through regional hubs of complex data transactions of demographic, clinical and genetic information, laboratory samples and results. Each registry has developed its own unique systems for representing data and process leading to transplantation. The WMDA Information Technology Working Group was formed in the autumn of 2001 as a forum to discuss and develop standards for information technology (IT) in support of hematopoietic stem cell registries. Its membership includes experts in IT from the WMDA member registries. The group has focused its standardization efforts on three areas:Standardized reference data sets for validation and plausibility controls for HLA and other data domainsMatching algorithm standards for determining histocompatibilityCommunication standards between registries. Bone Marrow Transplantation (2010) 45, 839-842; doi: 10.1038/bmt.2010.29; published online 1 March 2010