Association between physical and cognitive function in healthy elderly: The health, aging and body composition study
Association between physical and cognitive function in healthy elderly: The health, aging and body composition study
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DOI：
10.1159/000081043
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发表时间：
2005-01-01
影响因子：
5.7
通讯作者：
Newman, AB
中科院分区：
文献类型：
--
作者：
Rosano, C;Simonsick, EM;Newman, AB
在健康、衰老和身体成分研究中，对3,075名参与者的身体功能（步态速度、椅子站立、站立平衡）和认知功能[Teng改良的简易精神状态检查（3 MS）和数字符号替代测试（DSST）]进行了基线评估。每一个身体功能测量与认知功能的关联强度和幅度进行了检查。所有的身体功能指标都与3 MS和DSST评分相关（p < 0.001），在多变量分析中，每种关系都与参与者的人口统计学特征、体重、体力活动和共病健康状况无关。DSST的运动表现的相关性始终大于3 MS，并且在运动测试中，步态速度与独立于人口统计学、体重、体力活动和共病健康状况的认知测量保持显著相关。在这个大型的高功能老年人队列中，身体和认知功能之间的相关性并不完全由人口统计学解释。需要纵向研究来确定这种关系中因果关系的方向。版权所有（C）2005 S. Karger AG，巴塞尔。
Performance measures of physical function ( gait speed, chair stands, standing balance) and cognitive function [Teng-modified Mini-Mental Status Exam (3MS) and digit symbol substitution test (DSST)] were assessed at baseline in 3,075 participants in the Health, Aging and Body Composition Study. Each physical function measure was examined for the strength and magnitude of association with cognitive function. All physical function measures were associated with both the 3MS and DSST scores (p < 0.001), and in multivariate analysis each relationship was independent of demographic characteristics, weight, physical activity and comorbid health conditions of participants. The association of motor performance was consistently greater for the DSST than the 3MS and, among the motor tests, gait speed retained a significant association with both cognitive measures independent of demographic, weight, physical activity and comorbid health conditions. In this large cohort of high-functioning older adults, the correlation between physical and cognitive function was not entirely explained by demographics. Longitudinal studies are needed to determine the direction of causality in this relationship. Copyright (C) 2005 S. Karger AG, Basel.