Transcranial magnetic stimulation in therapy studies:: Examination of the reliability of "standard" coil positioning by neuronavigation
Transcranial magnetic stimulation in therapy studies:: Examination of the reliability of "standard" coil positioning by neuronavigation
复制标题
DOI：
10.1016/s0006-3223(01)01153-2
复制
发表时间：
2001-07-01
影响因子：
10.6
通讯作者：
Schönfeldt-Lecuona, C
中科院分区：
文献类型：
--
作者：
Herwig, U;Padberg, F;Schönfeldt-Lecuona, C
经颅磁刺激被认为是治疗抑郁症和其他精神疾病的一种新工具。在几乎所有的研究中，背外侧前额叶皮质(DLPFC)都被选为刺激的目标部位。通常，这一区域是通过识别患者的运动皮质来确定的，并从那里将线圈放置在吻部5厘米处。我们研究的目的是测试这一标准程序的可靠性。在将标准程序应用于个体皮质解剖后，使用神经导航系统来关联最终的线圈位置。在22名受试者中的7名，DLPFC的Brodman区9区以这种方式被正确定位。在15名受试者中，线圈的中心被发现位于更背部(例如，运动前皮质上方)。目前定位DLPFC的方法在解剖学上并不精确，可以通过考虑个体解剖的导航操作来改进。生物精神病学2001；50：58-61(C)2001生物精神病学学会。
Transcranial magnetic stimulation is investigated as a new tool in the therapy of depression and other psychiatric disorders. In almost all studies, the dorsolateral prefrontal cortex (DLPFC) has been selected as the target site for stimulation. Usually this region was determined by identifying the patient's motor cortex, and from there the coil was placed 5 cm rostrally. The aim of our study was to test the reliability of this standard procedure. A neuronavigational system was used to relate the final coil position after applying the standard procedure to the individual cortical anatomy. In 7 of 22 subjects, the Brodman area 9 of the DLPFC was targeted correctly in this manner. In 15 subjects, the center of the coil was found to be located more dorsally (e.g., above the premotor cortex). The current method for locating the DLPFC is not precise anatomically and may be improved by navigating procedures taking individual anatomy into account. Biol Psychiatry 2001;50:58-61 (C) 2001 Society of Biological Psychiatry.